0.05)。結(jié)論 聯(lián)用沙利度胺在類風(fēng)濕關(guān)節(jié)炎的治療中有積極作用。;Objective To systematically review the efficiency and safety of thalidomide combined with other drugs in the treatment of rheumatoid arthritis. Methods The randomized controlled trials (RCTs) about thalidomide treating rheumatoid arthritis were retrieved in the database of PubMed, Medline Web of science, CNKI, VIP, CBM, and Wanfang Data from the date of database foundation to August 2017. Meta-analysis was performed with state14.0 software. Results A total of 15 RCTs involving 1 246 patients were finally included; Meta-analysis results showed that, the effect of thalidomide combined with control was superior to control alone in the effective rate (OR=2.71, 95% CI=1.87-3.93, P<0.05), joint swelling number (OR=1.68, 95% CI=0.99-2.37, P<0.05), joint tenderness number(OR=2.22, 95% CI=1.31-3.14, P<0.05), and erythrocyte sedimentation rate (OR=12.93, 95% CI=10.26-15.60, P<0.05). There was no significant difference in the occurrence of adverse events between the thalidomide group and control group (OR=0.93, 95% CI=0.66-1.32, P>0.05). Conclusion Thalidomide combined with other drugs has a positive effect on the treatment of rheumatoid arthritis."/>

醉酒后少妇被疯狂内射视频,一本色道久久综合一,在线天堂新版资源www在线下载,中文字幕乱人伦高清视频,中字幕视频在线永久在线观看免费

首頁(yè) > 過(guò)刊瀏覽>2018年第41卷第5期 >2018,41(5):892-897,903. DOI:10.7501/j.issn.1674-6376.2018.05.e032
上一篇 | 下一篇

沙利度胺聯(lián)合其他藥品治療類風(fēng)濕關(guān)節(jié)炎的系統(tǒng)評(píng)價(jià)

Thalidomide combined with other drugs for treatment of rheumatoid arthritis: A systematic review

發(fā)布日期:2018-05-09
您是第位訪問(wèn)者
藥物評(píng)價(jià)研究 ® 2025 版權(quán)所有
技術(shù)支持:北京勤云科技發(fā)展有限公司
津備案:津ICP備13000267號(hào) 互聯(lián)網(wǎng)藥品信息服務(wù)資格證書(shū)編號(hào):(津)-非經(jīng)營(yíng)性-2015-0031