目的 研究銀杏內(nèi)酯注射液治療出血性腦梗死的安全性和有效性。方法 選取沈陽市第一人民醫(yī)院2016年1月-2017年12月收治的出血性腦梗死患者81例，隨機(jī)分為2組，對照組予以常規(guī)藥物治療，治療組在其基礎(chǔ)上加用銀杏內(nèi)酯注射液10 mL/次，生理鹽水250 mL稀釋，靜脈滴注，每天1次，連續(xù)使用14 d。觀察治療后的不良反應(yīng)、出血轉(zhuǎn)化情況，比較治療7、14、90 d后患者的美國國立衛(wèi)生研究院卒中量表（NIHSS）、mRS和ADL評分。結(jié)果 對照和治療組未出現(xiàn)藥物過敏及肝、腎功能惡化等不良反應(yīng)，影像學(xué)觀察未見出血擴(kuò)大，腦水腫明顯減輕。治療組和對照組在用藥7 d后各項評分指標(biāo)未見明顯統(tǒng)計學(xué)差異；而在治療14、90 d后，治療組的NIHSS評分、mRS評分較對照組顯著降低，ADL評分顯著提高，兩組差異具有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 銀杏內(nèi)酯注射液不會增加出血性腦梗死患者的出血擴(kuò)大，且能減輕腦水腫，改善患者神經(jīng)功能缺損，治療出血性腦梗死安全有效。

Objective To investigate the safety and efficacy of Ginkgolide Injection in treating hemorrhagic cerebral infarction.Methods Totally 81 patients with hemorrhagic cerebral infarction admitted to the first people's hospital of shenyang in January 2016 to December 2017 were randomly divided into two groups. The control group were treated with routine drugs, and the treatment group were treated with Ginkgolide Injection on the basis of routine drugs with 10 mL+0.9% NS, once daily for 14 d. The observation of the transformations of the hemorrhage and adverse reaction after treatment was carried out, and the comparation of the NIHSS, mRS and ADL scores of patients with treatment for 7, 14 and 90 d was done.Results No adverse reactions of drug allergy and deterioration of liver and kidney function were observed in the two groups. The imaging observation of treatment group showed no increase in hemorrhage, and the cerebral edema was significantly reduced. There was no statistically significant difference in the score indicators between treatment group and control group after 7 d of medication, The NIHSS scores and mRS scores of treatment group were significantly lower than those of control group, and the ADL scores were significantly improved, and the difference between the two groups was statistically significant (P < 0.05).Conclusion Ginkgolide Injection do not increase hemorrhage in patients with hemorrhagic cerebral infarction, and which can reduce cerebral edema, improve the neurological deficit of patients. Ginkgolide Injection is safe and effective in treating hemorrhagic cerebral infarction.