目的 探討桂枝茯苓丸聯(lián)合炔雌醇環(huán)丙孕酮片和枸櫞酸氯米芬膠囊對(duì)多囊卵巢綜合征后妊娠和心理狀態(tài)的影響。方法 以2012年2月-2016年2月佛山市中醫(yī)院收治的96例多囊卵巢綜合征患者為研究對(duì)象。按就診時(shí)間先后順序分為對(duì)照組和觀察組各48例。對(duì)照組給予炔雌醇環(huán)丙孕酮片和枸櫞酸氯米芬膠囊治療，觀察組在對(duì)照組治療基礎(chǔ)上加服桂枝茯苓丸。兩組均為21 d為1周期，6個(gè)周期為1療程。比較兩組治療前后的血清性激素、心理狀態(tài)和治療后1年內(nèi)的妊娠情況。結(jié)果 治療前，兩組的血清性激素水平差異無統(tǒng)計(jì)學(xué)意義；兩組治療后的血清性激素水平均低于治療前，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，觀察組的黃體生成素（LH）和睪酮（T）水平低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療前，兩組的SAS和SDS評(píng)分均無統(tǒng)計(jì)學(xué)差異；兩組治療后的SAS和SDS評(píng)分均低于治療前，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，觀察組的SAS和SDS評(píng)分均低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組的妊娠率和足月分娩率高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；兩組的流產(chǎn)率和早產(chǎn)率差異無統(tǒng)計(jì)學(xué)意義。結(jié)論 桂枝茯苓丸聯(lián)合炔雌醇環(huán)丙孕酮片和枸櫞酸氯米芬膠囊治療多囊卵巢綜合征，有利于調(diào)節(jié)血清性激素水平，提高妊娠率和足月分娩率，并可改善患者不良心理，值得臨床推廣。

objective To discuss the influence of Taie-35 and Clomifen combined with Laurel cocos poria pill on the pregnancy and psychological state of polycystic ovary syndrome patients.Methods A total of 96 polycystic ovary syndrome patients patientstreated in Foshan Hospital of TCM from February 2012 to February 2016 were studied and were divided into control group (48 cases) and observation group (48 cases) according to the time of admission. Control group received Taie-35 and Clomifen treatment. And observation group was treated with Laurel cocos poria pill on the base of control group. Serum sex hormone levels, psychological state and pregnancy of two groups were compared.Results Before treatment, the difference in serum sex hormone levels between two groups was not statistically significant. Serum sex hormone levels of two groups after treatment were lower than those before treatment (P < 0.05). After treatment, luteinizing hormone (LH) and testosterone (T) of observation group were lower than those of control group (P < 0.05). Before treatment, the differences in SAS and SDS scores between two groups were not statistically significant. SAS and SDS scores of two groups after treatment were lower than those before treatment (P < 0.05). After treatment, SAS and SDS scores of observation group were lower than those of control group (P < 0.05). After treatment, pregnancy rate and term delivery rate of observation group were higher than those of control group (P < 0.05). The differences in miscarriage rate and preterm birth rate between two groups were not statistically significant.Conclusion Taie-35 and Clomifen combined with Laurel cocos poria pill in treatment with polycystic ovary syndrome is helpful to adjust serum sex hormone level, increase pregnancy rate and term delivery rate, improve the patients' bad psychology and deserve clinical promotion.