+)、輔助性T細(xì)胞和遲發(fā)超敏性T細(xì)胞(CD3+CD4+)占淋巴細(xì)胞的比例(P<0.01)。結(jié)論 小分子阿膠能提高小鼠體液免疫和細(xì)胞免疫功能,對(duì)免疫功能有正向調(diào)節(jié)作用。;Objective To study the effect of small molecular Asini Corii Colla (SMACC) on immune function in mice. Methods ICR mice were randomly divided into control group, model group, Shengxue Pills (3.00 g/kg) group, and SMACC (3.00, 1.50, 0.75 g/kg) group, and they were ig administered for 14 d. Immunosuppressive model was established by intraperitoneal injection of cyclophosphamide or hydrocortisone. The use of red blood cells in chicken was to induce the production of hemolysin in mice. The content of serum hemolysin was measured to determine the effect of SMACC on humoral immunity. The ear swelling of mice was induced by two nitrochlorobenzene, and the auricular swelling of mice was detected to observe the effect of SMACC on cell immunity. Lymphocyte subsets in mice were analyzed by flow cytometry to observe the effect of SMACC on lymphocyte subtyping. Results Compared with model group, SMACC significantly increased the serum hemolysin content at doses of 3.00, 1.50, and 0.75 g/kg (P < 0.01), significantly increased the degree of auricular swelling in mice at doses of 3.00 and 1.50 g/kg (P < 0.01 and 0.05), and significantly promoted the proportion of T lymphocytes (CD3+), helper T cells, and delayed hypersensitivity T cells (CD3+CD4+) at doses of 3.00 g/kg (P < 0.01). Conclusions SMACC can enhance humoral immunity and cellular immune function in mice and has a positive regulatory effect on immune function in mice."/>