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[摘要]
目的 觀察注射用丹參多酚酸治療急性腦梗死患者的臨床療效。方法 選擇2017年11月-2018年6月在齊齊哈爾醫(yī)學院附屬第三醫(yī)院進行診治的急性腦梗死患者64例,隨機分為對照組與觀察組,各32例。對照組給予常規(guī)治療,觀察組在對照組基礎上加用注射用丹參多酚酸,每次0.13 g加入250 mL 0.9%氯化鈉中靜滴,1次/d,療程均為14 d。根據美國國立衛(wèi)生研究院卒中量表(NIHSS)判定臨床療效,以改良Rankin量表(mRS)評價神經功能恢復情況。結果 治療后,對照組與觀察組的有效率分別為75%和91%,觀察組的治療有效率明顯高于對照組(P<0.05);觀察組神經功能恢復明顯高于對照組(P<0.05)。結論 注射用丹參多酚酸治療急性腦梗死患者療效明顯,能促進神經功能改善,無明顯副作用,值得臨床推廣。
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[Abstract]
Objective To investigate the clinical effect of Salvianolic Acids for Injection (SAFI) in the treatment of acute cerebral infarction. Methods A total of 64 patients of acute cerebral infarction in The Third Affiliated Hospital of Qiqihar Medical College from November 2017 to June 2018 were selected and were randomly divided into the observation group and the control group. The patients in the control group received routine medicine therapy, and the patients in the treatment group was received SAFI 0.13 g added for 0.9% sodium chloride 250 mL intravenous drip qd in addition to the treatment of control group. Patients treated once per day and 14 d for one course of treatment, and the prognosis of the two groups were observed by NIHSS scores and mRS scores. Results The treatment efficiency in the observation group and control group respectively were 91% and 75%, and the observation group was significantly higher than that of the control group (P<0.05). The observation group significantly improve neurological function than that of the control group (P<0.05). Conclusion SAFI has good curative effect in the treatment of acute cerebral infarction, which can promote the improvement of neurological function, with no significant side effects, so it is worthy of clinical application.
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