目的 探討注射用丹參多酚酸治療急性腦梗死的臨床療效、安全性。方法 將80例急性腦梗死患者隨機(jī)分為觀察組（40例）和對(duì)照組（40例），對(duì)照組采用常規(guī)治療方法，阿司匹林腸溶片100 mg，每日1次，口服，瑞舒伐他汀鈣片10mg，每晚1次，口服，依達(dá)拉奉30 mg，每日2次，靜脈滴注；觀察組在對(duì)照組基礎(chǔ)上加用注射用丹參多酚酸100 mg，每日1次，靜脈滴注，療程14 d。兩組分別在治療前、后，對(duì)患者進(jìn)行美國(guó)國(guó)立衛(wèi)生院神經(jīng)功能缺損程度評(píng)分（NHISS），日常生活活動(dòng)能力量表評(píng)分（Barthel指數(shù)），檢測(cè)血清C反應(yīng)蛋白水平。結(jié)果 觀察組總有效率為87.5%，對(duì)照組總有效率為57.5%，兩組治療臨床效果比較差異顯著（P<0.05）；治療后，兩組患者NIHSS評(píng)分、C反應(yīng)蛋白水平明顯降低，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組顯著低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組患者Barthel指數(shù)明顯升高，同組治療前后比較差異有統(tǒng)計(jì)學(xué)意義（P<0.05）；且觀察組顯著高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。觀察組僅1例出現(xiàn)短暫性面紅情況，減慢靜滴速度后消失。兩組肝功及心肌酶均在正常范圍。結(jié)論 注射用丹參多酚酸治療急性腦梗死療效顯著、安全性好。

Objective To investigate the clinical efficacy and safety of Salvianolic Acid for Injection in the treatment of acute cerebral infarction. Methods Tatolly 80 patients with acute cerebral infarction were randomly divided into observation group (40 cases) and control group (40 cases). The control group was treated with routine therapy, Aspirin enteric-coated tablets 100 mg, once a day, oral, rosuvastatin calcium tablets 10 mg, once a night, oral, edaravone 30 mg, twice a day, static. Pulse drip, the observation group on the basis of the control group with Salvianolic Acid for Injection 100 mg, once a day, intravenous drip, 14 days for a course of treatment, the two groups before and after treatment, the patients with neurological deficit score (NHISS score), activity of daily living scale score (Barthel Index). Results Compared with the control group, the total effective rate was 87.5% in the observation group and 57.5% in the control group, and the clinical effect was compared between the two groups (P<0.05). After treatment, the NIHSS score and C-reactive protein level of the two groups were significantly lower than those of the control group (P<0.05), and the observation group was significantly lower than that of the control group (P<0.05). After treatment, the Barthel index of the two groups increased significantly, and there was significant difference before and after treatment in the same group (P<0.05); and the observation group was significantly higher than the control group, the difference was statistically significant (P<0.05). In the observation group, only one case had transient blush, which disappeared after slowing down the intravenous drip speed. The liver function and myocardial enzymes in both groups were in normal range. Conclusion salvianolic acid injection is effective and safe in the treatment of acute cerebral infarction.