目的 考察青海省人民醫(yī)院高同型半胱氨酸（Hcy）血癥患者藥物干預(yù)的合理性，為臨床合理使用藥物治療高Hcy血癥患者提供參考。方法 抽取2015年1-3月青海省人民醫(yī)院診斷為高Hcy血癥的住院患者273例，考察Hcy水平與收縮壓、舒張壓、年齡之間的差異及各科室治療高Hcy血癥藥物的合理性。結(jié)果 Hcy與年齡、收縮壓和舒張壓不存在相關(guān)性。273例高Hcy血癥血癥患者基礎(chǔ)疾病主要為心血管系統(tǒng)疾病、代謝性疾病及神經(jīng)系統(tǒng)疾病，占88.67%。273例高Hcy血癥患者藥物干預(yù)率為72.5%。結(jié)論 青海省人民醫(yī)院各科使用降Hcy藥物存在不合理現(xiàn)象。合理補充葉酸、維生素B₆和維生素B₁₂可降低血漿Hcy水平，治療Hcy合并原發(fā)性疾病的臨床療效顯著。

Objective To investigate the correlation between homocysteine (Hcy) and blood pressure and age for patients, evaluate the rationality of drug intervention in patients with homocysteinemia in our hospital, and to treat patients with high homocysteine Patients with hematuria to provide a reference.Methods A total of 273 in patients who were diagnosed with hyperhomocysteinemia (HHcy) from January to March 2015 were enrolled in this study. The differences of Hcy levels with systolic blood pressure, diastolic blood pressure and age were investigated. Rationality of Drug Selection for Hyperhomocysteinemia.Results Of the 273 patients, 75 were not treated with drugs, and cardiovascular disease, metabolic diseases and neurological diseases accounted for 88.67%. Systolic blood pressure, diastolic blood pressure were no significant difference between the P values were 0.641, and 0.354. Conclusion Supplementation of small doses of folic acid and vitamin B₁₂ can be used in patients with hyperhomocysteinemia.