[關(guān)鍵詞]
[摘要]
近10年來,新發(fā)現(xiàn)了36種中藥活性成分(部位)能夠有效保護(hù)損傷心肌,分別通過調(diào)控凋亡基因的表達(dá)、調(diào)節(jié)氧化應(yīng)激、抑制炎癥反應(yīng)等發(fā)揮對(duì)損傷心肌的保護(hù)作用。對(duì)此做系統(tǒng)論述及整理,為心血管領(lǐng)域的新藥研發(fā)提供參考。
[Key word]
[Abstract]
This article summarizes the recent progress in the research on the active ingredients and mechanism of Chinese medicine protecting injured myocardium in the past 10 years. And 36 kinds of active ingredients of traditional Chinese medicine have been found to effectively protect injured myocardium. They play injured myocardium intervention by regulating the expression of apoptosis gene and the oxidative stress and inhibiting inflammatory reaction. This paper makes a systematic discussion and collation.
[中圖分類號(hào)]
[基金項(xiàng)目]
國家自然科學(xué)基金項(xiàng)目(81173164及81573852)