清金化痰湯是治療咳嗽屬痰熱壅肺證具有明顯特色與優(yōu)勢(shì)的經(jīng)典名方，在感染性肺系疾病如慢阻肺急性加重期、急性支氣管炎、慢性支氣管炎急性發(fā)作期、肺炎、支氣管擴(kuò)張等中廣泛應(yīng)用。總結(jié)該方主治病證及適應(yīng)癥、處方功效、古方現(xiàn)代研究進(jìn)展和臨床應(yīng)用進(jìn)展，并以AECOPD為例研究清金化痰湯在感染性肺系病中的應(yīng)用情況，確認(rèn)本方傳統(tǒng)功效與現(xiàn)代適應(yīng)癥有較好的對(duì)應(yīng)關(guān)系，且有嚴(yán)格設(shè)計(jì)的臨床研究和有效性的充分證據(jù)，是值得深入研究和開(kāi)發(fā)的經(jīng)典古方。

Qingjin Huatan Decoction is a classical herbal formulae with obvious characteristics and advantages in the treatment of cough with phlegm-heat obstructing lung syndrome. It is widely used in infectious pulmonary diseases such as AECOPD, acute bronchitis, acute attack of chronic bronchitis, pneumonia and bronchiectasis. This paper summed up the party primary healing and the recipe of indications, efficacy, the viewpoints of modern research progress and clinical application progress, as a case study of AECOPD study Qingjin Huatan Decoction in the application of the department of infectious lung disease, confirming their traditional and modern efficacy indications have good corresponding relationships, and there is sufficient evidence of rigorously designed clinical research and effectiveness. It is classical herbal formulae worthy of in-depth research and development.

國(guó)家重大新藥創(chuàng)制科技專項(xiàng)（2018ZX09721004-006）