氧化苦參堿治療病毒性和非病毒性肝損傷有效，其能增強拉米夫定、干擾素或甘草酸類藥物治療病毒性肝炎和肝纖維化的臨床療效。氧化苦參堿除了直接的抗病毒、抗炎、肝臟保護作用外，還可通過提高患者的免疫調(diào)節(jié)功能，間接增強機體清除和抑制病毒。這些作用可能是氧化苦參堿治療肝炎和肝纖維化的作用機制。

Oxymatrine has clinical efficacy for the treatment of viral and non-viral liver injuries. Oxymatrine improves the clinical efficacy of lamivudine, interferon, or glycyrrhizic acid-type compounds for the treatment of viral hepatitis, and hepatic fibrosis. Except direct effects of anti-virus, anti-inflammation, and hepatoprotection, oxymatrine indirect promotes ability of body to inhibit and eliminate virus by increasing immunoregulation of patient. These may be the effective mechanism of oxymatrine for the treatment hepatitis and hepatic fibrosis.