目的 觀察注射用丹參多酚酸治療急性腦梗死的臨床療效。方法 選取2017年6月—2018年6月安陽市第六人民醫(yī)院治療的急性腦梗死患者200例作為研究對(duì)象，將患者分為對(duì)照組和觀察組，每組各100例。對(duì)照組給予抗血小板聚集、清除及抗自由基等治療腦梗死的常規(guī)藥物治療，觀察組在對(duì)照組治療的基礎(chǔ)上靜脈滴入注射用丹參多酚酸，130 mg稀釋于0.9%氯化鈉溶液250 mL，1次/d。兩組均治療2周。比較兩組患者治療前后的美國國立衛(wèi)生研究院卒中量表（NIHSS）和日常生活活動(dòng)能力（ADL）評(píng)分，并觀察兩組患者的臨床療效。結(jié)果 治療后，兩組NIHSS評(píng)分明顯下降，ADL評(píng)分明顯提升，同組治療前后比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，觀察組NIHSS評(píng)分明顯低于對(duì)照組，ADL評(píng)分明顯高于對(duì)照組，兩組比較差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，觀察組總有效率為95%，明顯高于對(duì)照組的71%（P<0.05）。結(jié)論 注射用丹參多酚酸應(yīng)用于急性腦梗死患者的治療療效確定，可在很大程度上改善患者肢體運(yùn)動(dòng)功能和神經(jīng)功能，提高日常生活質(zhì)量，值得臨床廣泛推廣使用。

Objective To observe the clinical effect of Salvianolic Acids for injection on acute cerebral infarction. Methods Patients (200 cases) with acute cerebral infarction in Anyang People's Hospital NO.6 from June 2017 to June 2018 were randomly divided into control and observation group, and each group had 100 cases. Patients in the control group was treated with conventional drugs for treating cerebral infarction, such as anti-platelet aggregation, scavenging and anti-free radical. Patients in the observation group were iv administered with Salvianolic Acids for injection on the basis of control group, 130 mg diluted in 0.9% sodium chloride solution 250 mL, once daily. Patients were treated for 2 weeks. The NIHSS and ADL scores before and after treatment were compared between two groups, and the clinical efficacy of the two groups was observed. Results After treatment, the NIHSS score in two groups were significantly decreased, but the ADL score were increased, the difference between two groups before and after treatment was statistically significant (P < 0.05). After treatment, NIHSS score in the observation group was significantly lower than that in the control group, and the ADL score was significantly higher than that in the control group, the difference between two groups was statistically significant (P < 0.05). After treatment, the total effective rate of observation group was 95%, which was significantly higher than 71% in the control group (P < 0.05). Conclusion The therapeutic effect of Salvianolic Acids for injection in treatment of acute cerebral infarction can be determined, which can greatly improve the limb motor function and nerve function of patients, improve the quality of daily life, and is worthy of widespread clinical use.

R969.4