目的 研究蟬花子實體的抗疲勞、增強(qiáng)運(yùn)動耐力作用。方法 ICR雄性小鼠隨機(jī)分為對照組、人參乙醇提取物（陽性藥，2.5 g/kg）組以及蟬花子實體低、中、高劑量（0.075、0.150、0.300 g/kg）組，連續(xù)ig給藥15 d后，測定小鼠負(fù)重游泳力竭時間，試劑盒法檢測小鼠經(jīng)游泳運(yùn)動后肝糖原、肌糖原、全血乳酸（LD）、血清尿素氮（BUN）、超氧化歧化酶（SOD）和乳酸脫氫酶（LDH）等與疲勞相關(guān)聯(lián)的生化指標(biāo)變化。結(jié)果 與對照組比較，蟬花子實體低、中劑量對小鼠力竭游泳時間有顯著延長作用（P<0.05），低劑量組LD水平顯著下降（P<0.05），高劑量LDH含量顯著升高（P<0.05），低劑量組SOD含量顯著升高（P<0.05）；中、高劑量組BUN含量顯著降低（P<0.05），低劑量組肝糖原水平顯著升高（P<0.05）；中劑量組肌糖原水平顯著升高（P<0.05）。結(jié)論 蟬花子實體對運(yùn)動后的小鼠有抗疲勞作用。

Objective To study cicadae anti-fatigue and enhance exercise endurance effects. Methods ICR male mice were randomly divided into different groups, control group, the ginseng group, cicadae high, medium and low dose (0.075, 0.150, and 0.300 g/kg) group, continuous ig administration of 15 d, different groups were measured by loading swimming time, liver glycogen, muscle glycogen, blood urea nitrogen (BUN), blood lactic acid (LD), superoxide dismutase (SOD) and lactate dehydrogenase (LDH), fatigue associated with changes in biochemical markers. Results Compared with the control group, the low and middle dose of Cicada flower body significantly prolonged the exhaustive swimming time of mice (P<0.05), the level of LD in the low dose group significantly decreased (P<0.05), the content of LDH in the high dose group significantly increased (P<0.05), the content of SOD in the low dose group significantly increased (P<0.05), the content of BUN in the middle and high dose groups significantly decreased (P<0.05), and the level of liver glycogen in the low dose group significantly increased (P<0.05). In the middle dose group, the level of muscle glycogen was significantly increased (P<0.05). Conclusion Cicada flower fruiting body has anti-fatigue effect on mice after exercise.

R285.5

國家星火計劃（2015GA700011）