[關(guān)鍵詞]
[摘要]
植物代謝組學(xué)技術(shù)是借助多種檢測(cè)手段以植物提取物中代謝物為研究對(duì)象進(jìn)行全面定性、定量分析,繼基因組學(xué)和蛋白質(zhì)組學(xué)之后發(fā)展起來(lái)的一門新興學(xué)科。隨著核磁共振(NMR)、液相色譜-質(zhì)譜聯(lián)用(LC-MS)、氣相色譜-質(zhì)譜聯(lián)用(GC-MS)等技術(shù)的快速發(fā)展,植物代謝組學(xué)已廣泛應(yīng)用于中藥資源研究中。對(duì)該技術(shù)在中藥基原鑒別、野生與栽培品的鑒別、藥用部位鑒別、不同發(fā)育期的成分鑒定及不同產(chǎn)地藥材的品質(zhì)差異等方面研究進(jìn)展進(jìn)行綜述,從而揭示植物代謝物動(dòng)態(tài)變化趨勢(shì),為中藥質(zhì)量評(píng)價(jià)奠定基礎(chǔ)。
[Key word]
[Abstract]
Plant metabolomics is a comprehensive qualitative and quantitative analysis of metabolites in plant extracts using a variety of detection methods. It is an emerging discipline developed after genomics and proteomics. With the rapid development of nuclear magnetic resonance (NMR), liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS) and other technologies, plant metabolomics has been widely used in the research of traditional Chinese medicine resources. This article reviews the application of plant metabolomics technology in the use of resources of traditional Chinese medicine, planting, medicinal parts, place of origin, harvest time and different development stages of traditional Chinese medicine, so as to reveal the dynamic changes of plant metabolites and lay the foundation for the quality evaluation of traditional Chinese medicine basis.
[中圖分類號(hào)]
R965.2
[基金項(xiàng)目]