氧化苦參堿能抑制疤痕成纖維細(xì)胞增殖和膠原合成，并誘導(dǎo)凋亡和基質(zhì)金屬蛋白酶表達(dá)。氧化苦參堿能抑制皮膚癌細(xì)胞增殖并誘導(dǎo)凋亡，也能抑制表皮角質(zhì)形成細(xì)胞增殖和黑素形成。氧化苦參堿對(duì)各種免疫性和非免疫性皮膚炎癥均有抗炎作用，臨床上已被試用于多種皮膚病的治療。

Oxymatrine inhibits proliferation and collagen synthesis of scar fibroblasts, and induces apoptosis and expression of MMP. Oxymatrine inhibits proliferation and induces apoptosis of skin carcinoma cells, and too inhibits proliferation of epidermic keratinocyte and melanogenesis. Oxymatrine has anti-inflammatory effects against various immune and non-immune dermatitis. In clinic Oxymatrine has been tried on the treatment of various dermatitis.

R285.5;R287.6