[關(guān)鍵詞]
[摘要]
藤苦參Streptocaulon griffithii是我國(guó)傣族傳統(tǒng)用藥,在民間應(yīng)用廣泛,極具開發(fā)前景。藤苦參含有多種生物活性成分,包括強(qiáng)心甾、三萜、有機(jī)酸、木脂素、苯環(huán)衍生物等。藥理研究表明,藤苦參及其有效成分具有顯著的抗腫瘤、促進(jìn)創(chuàng)傷愈合、抗癲癇等藥理作用。對(duì)藤苦參化學(xué)成分及藥理作用進(jìn)行綜述,旨在為進(jìn)一步開發(fā)和臨床應(yīng)用提供參考。
[Key word]
[Abstract]
Streptocaulon griffithii is a widely used traditional Chinese medicine of Dai nationality with broad development prospects. Streptocaulon griffithii contains various biologically active constituents, including cardiotonic steroids, triterpenoids, organic acids, lignans, benzene ring derivatives and so on. Pharmacological researches showed that Streptocaulon griffithii and its active components exerted significant anti-tumor, wound healing and anti-epileptic activities. The chemical constituents and pharmacological activities of Streptocaulon griffithii were reviewed to provide references for the further development of Streptocaulon griffithii and its clinical application.
[中圖分類號(hào)]
R284.2;R285.5
[基金項(xiàng)目]
國(guó)家自然科學(xué)基金(81973565);國(guó)家重大新藥創(chuàng)制專項(xiàng)(2017ZX09301005)