目的 建立電感耦合等離子體光譜法（ICP-OES）測定特靈眼藥中鐵（Fe）、鉛（Pb）、鈣（Ca）、鋁（Al）、鎂（Mg）、硼（B）、鈉（Na）含量。方法 采用微波消解法對(duì)樣品進(jìn)行前處理，電感耦合等離子體發(fā)射光譜法測定特靈眼藥中Fe、Pb、Ca、Al、Mg、B、Na含量。結(jié)果 Fe、Pb、Ca、Al、Mg、B、Na線性范圍為0.1~50.0 μg/mL（r=0.993 0~0.999 9）；檢測限為0.591 2~45.867 9 mg/kg；重復(fù)性試驗(yàn)的RSD均小于6%；加樣回收率為101.1%~110.0%，RSD為4.4%~5.7%，均小于6%。結(jié)論 該方法操作簡便、準(zhǔn)確，重復(fù)性好，可用于特靈眼藥中鐵、鉛、鈣等7種金屬元素含量的同時(shí)測定。

Objective An ICP-OES method was established for the determination of Fe、Pb、Ca、Al、Mg、B、Na in Teling Ophthalmic Remedy. Methods The sample was pretreated by microwave digestion method, and the contents of Fe, Pb, Ca, Al, Mg, B, Na in Teling Ophthalmic Remedy were determined by ICP-OES method. Results The linear range of Fe, Pb, Ca, Al, Mg, B, Na concentration was 0.1-50.0 μg/mL(r=0.993 0-0.999 9), the detection limit was 0.591 2-45.867 9 mg/kg, the RSD of the repeated tests was less than 6%. The recoveries were 101.1%-110.0%, and RSD was 4.4%-5.7%, was less than 6%. Conclusions The method is simple, accurate and reproducible. It can be used for simultaneous determination of Fe, Pb, Ca, and other 7 metal elements in Teling Ophthalmic Remedy.

R988.1;R927.2

河北省科技計(jì)劃項(xiàng)目（17272504D）