5-羥甲基糠醛（5-HMF）是中藥中廣泛存在的化學(xué)成分，在中藥炮制、貯藏、配伍過程中含量變化明顯。現(xiàn)代藥理學(xué)研究表明5-HMF具有抗氧化、改善學(xué)習(xí)記憶、抗過敏、保護(hù)神經(jīng)細(xì)胞、抗炎等藥理作用。結(jié)合國內(nèi)外有關(guān)文獻(xiàn)，對(duì)5-HMF在中藥道地性、炮制加工、貯藏方面的含量變化及藥理作用進(jìn)行綜述，以期為提升中藥材質(zhì)量標(biāo)準(zhǔn)和臨床合理用藥提供參考。

5-Hydroxymethyl furfural (5-HMF) is a relatively wide range of chemical constituents in traditional Chinese medicine. Its content changes significantly during the processing, storage, and compatibility of traditional Chinese medicine. Modern pharmacological studies have shown that 5-HMF has anti-oxidation, improve learning and memory, anti-allergy, protect nerve cells, anti-infla matory and other pharmacological effects. This article summarizes the content changes and pharmacological effects of 5-HMF in the authenticity, processing andstorage of traditional Chinese medicine in combination with relevant literatureathome and abroad, in order to provide a reference for improving the quality standards of traditional Chinese medicine and clinical rational use of medicine.

R283.1;R285.5

山西省中醫(yī)藥中老年健康產(chǎn)業(yè)技術(shù)創(chuàng)新聯(lián)盟項(xiàng)目（JKCY201904）；2020年度山西省研究生教育創(chuàng)新項(xiàng)目（2020SY460）；山西省中醫(yī)藥研究院院級(jí)課題（201905）；山西中醫(yī)藥大學(xué)學(xué)科建設(shè)項(xiàng)目（1008Z4）；2020年山西中醫(yī)藥大學(xué)校級(jí)研究生創(chuàng)新項(xiàng)目（2020CX039）