細(xì)胞治療作為新興的現(xiàn)代生物醫(yī)學(xué)技術(shù)，促進(jìn)了以精準(zhǔn)醫(yī)學(xué)和系統(tǒng)生物學(xué)為代表的治療變革，也不斷地與中醫(yī)關(guān)于生命認(rèn)識(shí)的整體觀和"天人合一"的思維接近。細(xì)胞治療為腫瘤等多種疾病的治療提供了新的策略，但其不良反應(yīng)和應(yīng)用局限制約了其在臨床上的廣泛應(yīng)用。中醫(yī)藥與細(xì)胞治療聯(lián)合使用，發(fā)揮協(xié)同作用，在提高細(xì)胞治療療效、減輕毒副作用方面已經(jīng)做了一些探索和嘗試。概述中醫(yī)藥在免疫細(xì)胞治療、干細(xì)胞治療和基因修飾體細(xì)胞治療中的應(yīng)用現(xiàn)狀，初步探討中醫(yī)藥聯(lián)合細(xì)胞治療在未來(lái)的發(fā)展趨勢(shì)。

As an emerging modern biomedical technology, cell therapy has promoted the therapeutic revolution represented by precision medicine and systematic biology, and is also close to the concept of the holistic view of life understanding and "harmony between man and nature" in traditional Chinese medicine. Cell therapy provides a new strategy for the treatment of many diseases such as tumors, but its adverse reactions and application limitations restrict its wide application in clinic. Combined use of traditional Chinese medicine and cell therapy plays a synergistic role, and some explorations and attempts have been made to improve the efficacy of cell therapy and reduce the toxic and side effects. This paper summarizes the application of TCM in immune cell therapy, stem cell therapy and genetically modified somatic cell therapy, and discusses the development trend of TCM combined cell therapy in the future.

R926

國(guó)家科技重大專(zhuān)項(xiàng)課題——重大新藥創(chuàng)制（2016ZX09101094）；北京市科委企業(yè)技術(shù)創(chuàng)新平臺(tái)建設(shè)（Z181100000518028）