細胞治療作為新興的現(xiàn)代生物醫(yī)學技術(shù)，促進了以精準醫(yī)學和系統(tǒng)生物學為代表的治療變革，也不斷地與中醫(yī)關(guān)于生命認識的整體觀和"天人合一"的思維接近。細胞治療為腫瘤等多種疾病的治療提供了新的策略，但其不良反應(yīng)和應(yīng)用局限制約了其在臨床上的廣泛應(yīng)用。中醫(yī)藥與細胞治療聯(lián)合使用，發(fā)揮協(xié)同作用，在提高細胞治療療效、減輕毒副作用方面已經(jīng)做了一些探索和嘗試。概述中醫(yī)藥在免疫細胞治療、干細胞治療和基因修飾體細胞治療中的應(yīng)用現(xiàn)狀，初步探討中醫(yī)藥聯(lián)合細胞治療在未來的發(fā)展趨勢。

As an emerging modern biomedical technology, cell therapy has promoted the therapeutic revolution represented by precision medicine and systematic biology, and is also close to the concept of the holistic view of life understanding and "harmony between man and nature" in traditional Chinese medicine. Cell therapy provides a new strategy for the treatment of many diseases such as tumors, but its adverse reactions and application limitations restrict its wide application in clinic. Combined use of traditional Chinese medicine and cell therapy plays a synergistic role, and some explorations and attempts have been made to improve the efficacy of cell therapy and reduce the toxic and side effects. This paper summarizes the application of TCM in immune cell therapy, stem cell therapy and genetically modified somatic cell therapy, and discusses the development trend of TCM combined cell therapy in the future.

R926

國家科技重大專項課題——重大新藥創(chuàng)制（2016ZX09101094）；北京市科委企業(yè)技術(shù)創(chuàng)新平臺建設(shè)（Z181100000518028）