目的 寧泌泰膠囊聯(lián)合左氧氟沙星治療細(xì)菌性前列腺炎的臨床療效。方法 選取2018年1月-2019年9月安徽醫(yī)科大學(xué)安慶附屬醫(yī)院收治的62例細(xì)菌感染性前列腺炎患者作為研究對(duì)象，根據(jù)治療方案的不同將患者分為對(duì)照組和觀察組，每組31例。對(duì)照組患者靜脈滴注鹽酸左氧氟沙星注射液，0.4 g/d；觀察組在對(duì)照組基礎(chǔ)上口服寧泌泰膠囊，3粒/次，3次/d。兩組患者均治療2周。觀察兩組患者的臨床療效，同時(shí)比較兩組治療前后尿液、前列腺液中白細(xì)胞數(shù)量和美國(guó)國(guó)立衛(wèi)生研究院前列腺炎癥狀指數(shù)（NIH-CPSI）評(píng)分。結(jié)果 治療后，觀察組總有效率為93.54%，顯著高于對(duì)照組的77.42%，差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療后，兩組尿液和前列腺液白細(xì)胞數(shù)量顯著下降，差異具有統(tǒng)計(jì)學(xué)意義（P<0.01）；觀察組治療后尿液和前列腺液白細(xì)胞數(shù)量顯著低于對(duì)照組，差異具有統(tǒng)計(jì)學(xué)意義（P<0.01）。兩組患者治療后NIH-CPSI評(píng)分均顯著下降，差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）；治療后，觀察組NIH-CPSI評(píng)分顯著低于對(duì)照組，差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。治療過程中，觀察組惡心嘔吐、腹痛腹瀉發(fā)生例數(shù)均顯著低于對(duì)照組，差異具有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 寧泌泰膠囊聯(lián)合左氧氟沙星治療細(xì)菌性前列腺炎具有較好的臨床療效，不良反應(yīng)發(fā)生率較低，值得臨床推廣。

Objective To investigate the clinical efficacy of Ningmitai Capsules combined with levofloxacin in treatment of bacterial infectious prostatitis. Methods A total of 62 patients with bacterial prostatitis admitted to Anqing Affiliated Hospital of Anhui Medical University from January 2018 to September 2019 were selected as the study subjects. According to different treatment regiments, the patients were divided into control group and observation group, with 31 patients in each group. Patients in the control group were intravenously injected with Levofloxacin Hydrochloride Injection, 0.4 g/d. Patients in the observation group were po administered with Ningmitai Capsules on the basis of control group, 3 tablets/time, three times daily. Patients in two groups were treated for two weeks. The clinical efficacy in two groups was observed, and the count of white blood cells in urine and prostatic fluidwhite, and NIH-CPSI score before and after treatment in two groups were compared. Results After treatment, the total effective rate of the control group was 93.54%, which was significantly higher than 77.42% of control group, with statistically significant difference (P<0.05). After treatment, the number of white blood cells in urine and prostatic fluid of two groups was significantly decreased (P<0.01). After treatment, the number of white blood cells in urine and prostatic fluid in the observation group was significantly lower than those in the control group, and the difference was statistically significant (P<0.01). After treatment, NIH-CPSI scores were significantly decreased in two groups, and the difference was statistically significant (P<0.05). After treatment, the NIH-CPSI score in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). During the treatment, the number of nausea and vomiting, abdominal pain and diarrhea in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion Ningmitai Capsules combined with levofloxacin in treatment of bacterial prostatitis has a good clinical effect, the incidence of adverse reactions is low, worthy of clinical promotion.

R983