芪參益氣滴丸是由黃芪、丹參、三七、降香組成的復(fù)方制劑，具有補氣活血、化瘀的功效。其藥理作用主要包括抗炎、抗氧化應(yīng)激、抑制纖維化、抗凋亡、促血管生成、改善能量代謝、抗血小板等，在冠心病、冠狀動脈血運重建術(shù)后、高血壓合并心臟病、糖尿病合并心臟病等心血管疾病方面有較好的應(yīng)用前景。從藥理作用、臨床應(yīng)用方面研究進展總結(jié)芪參益氣滴丸的心血管保護特性，以期為該制劑的深度開發(fā)及臨床合理用藥提供理論支持。

Qiushen Yiqi Dropping Pill (QYDP) is a compound preparation composed of Astragalus membranaceus, Salvia miltiorrhiza, Panax notoginseng, and Dalbergia odorifera, which has the effect of invigorating qi and promoting blood circulation and removing blood stasis. Its pharmacological effects mainly include anti-inflammatory, anti-oxidative stress, inhibition of fibrosis, anti-apoptosis, promotion of angiogenesis, improvement of energy metabolism, anti-platelet, and so on. It has a good application prospect in coronary heart disease, coronary artery revascularization, hypertension with heart disease, diabetes with heart disease, and other cardiovascular diseases. The cardiovascular protective properties of QYDP were summarized from the aspects of pharmacology and clinical application to provide theoretical support for the in-depth development and rational clinical use of this preparation.

R287.5

國家自然科學基金資助項目（81873149）；國家科技重大專項重大新藥創(chuàng)制項目（2018ZX09734-002）