葛根Pueraria lobata是藥食同源中藥，具有多種功效?，F(xiàn)代藥學(xué)研究表明異黃酮類是葛根的主要活性成分，已經(jīng)分離到53個葛根異黃酮化合物，包括葛根素、大豆苷元、大豆苷、葛根素木糖苷、3'-羥基葛根素、染料木素、染料木苷、鷹嘴豆芽素A、芒柄花素、毛蕊異黃酮等，具有解酒護肝、降血糖、調(diào)血脂、緩解絕經(jīng)性骨質(zhì)疏松、抗腫瘤、心臟保護、抗炎、神經(jīng)保護、抗氧化等藥理作用。對葛根異黃酮類的藥理作用進行綜述，以期為該類成分的進一步研究和新藥研發(fā)提供參考。

Pueraria lobata is a homology of medicine and food with multiple effects. Modern pharmacological investigations demonstrate that isoflavones are the main active components of P. lobata. And it was reported that 53 isoflavone compounds had been isolated from the root of P. lobata, including puerarin, daidzein, daidzin, puerarin xyloside, 3'-hydroxypuerarin, genistein, genistin, biochanin A, formononetin, calycosin, and so on. They have pharmacological effects such as antialcoholism, liver protection, hypoglycemia, lipid-lowering, menopausal osteoporosis relief, anti-tumor, heart protection, anti-inflammatory, neuroprotection and anti-oxidation. This paper reviews the pharmacological effects of isoflavones from P. lobata, which provides reference for further research and new drug development of this kind of components.

R285.5

江西省農(nóng)業(yè)農(nóng)村廳現(xiàn)代農(nóng)業(yè)產(chǎn)業(yè)技術(shù)體系建設(shè)專項(JXARS-16)