[關鍵詞]
[摘要]
為了解黃芩的研究現(xiàn)狀、研究熱點,為后續(xù)的研究提供直觀的數(shù)據(jù)參考依據(jù)和相關建議,檢索2000年1月1日—2022年6月30日萬方數(shù)據(jù)庫(Wanfang Data)、中國學術期刊全文數(shù)據(jù)庫(CNKI)、維普生物醫(yī)學數(shù)據(jù)庫(VIP)、中國生物醫(yī)學文獻數(shù)據(jù)庫(CBM)、Web of Science(WOS)數(shù)據(jù)庫以及PubMed醫(yī)學文獻檢索服務系統(tǒng)中關于黃芩的文獻,通過VOS viewer軟件呈現(xiàn)可視化圖譜進行文獻計量分析。結果顯示,22年來黃芩發(fā)文量呈波動上升趨勢;中英文關鍵詞聚類分析顯示,目前對黃芩的研究以化學成分、藥理作用、臨床應用為主;關鍵詞疊加時間可視化圖譜顯示黃芩-黃連藥對治療2型糖尿病、黃芩治療新型冠狀病毒肺炎(COVID-19)是有關黃芩的研究前沿內容;網(wǎng)絡藥理學與分子對接技術是探究藥效物質基礎的新方法。
[Key word]
[Abstract]
In order to understand the research status and research hotspots of Scutellariae Radix, and provide intuitive data reference and related suggestions for subsequent research, the literature on Scutellariae Radix in Wanfang Database (Wanfang Data), China Academic Journal Full-text Database (CNKI), VIP Biomedical Database (VIP), China Biomedical Literature Database (CBM), Web of Science (WOS) database and PubMed medical literature retrieval service system from January 1, 2000 to June 30, 2022 were searched. Bibliometric analysis was performed by presenting a visual map through VOS viewer software. The results showed that the number of published articles of Scutellariae Radix increased with fluctuation in 22 years. Cluster analysis of Chinese and English keywords showed that the current research on Scutellariae Radix was mainly based on chemical composition, pharmacological action and clinical application. The visualization map of keyword superposition time showed that the treatment of type 2 diabetes mellitus by Scutellariae Radix-Coptidis Rhizoma drug pair and the treatment of novel coronavirus pneumonia (COVID-19) by Scutellariae Radix were the research frontiers of Scutellariae Radix. Network pharmacology and molecular docking technology are new methods to explore the pharmacodynamic material basis.
[中圖分類號]
[基金項目]
中央引導地方科技發(fā)展資金資助項目(206Z2501G);河北省重點研發(fā)計劃項目(20372502D)