萬(wàn)年蒿 Artemisia sacrorum 是中國(guó)東北地區(qū)的習(xí)用藥材,有清熱解毒、涼血止血、止痛的功效?，F(xiàn)代藥理學(xué)研究表明,萬(wàn)年蒿及其有效成分在保肝、抗癌、抗腫瘤、抗炎、抗肥胖、抗菌、抗氧化、鎮(zhèn)痛等方面具有良好的藥理活性,同時(shí)對(duì)萬(wàn)年蒿防治肝損傷、抗癌、抗炎、抗肥胖等的作用機(jī)制進(jìn)行了研究。隨著蒿屬植物研究的深入,萬(wàn)年蒿作為常用的蒿屬植物得到了更多的關(guān)注。對(duì)萬(wàn)年蒿及其有效成分的藥理作用進(jìn)行綜述,以期為進(jìn)一步利用、質(zhì)量控制以及新藥研發(fā)提供依據(jù)。

Artemisia sacrorum Ledeb. is a medicine herb used in Northeast China. It has the functions of clearing heat and detoxifying, cooling blood to stop bleeding and relieving pain. Modern pharmacological research shows that A. sacrorum and its active ingredients in hepatoprotective, anti-tumor, anti-inflammatory, anti-obesity, antibacterial, antioxidant, analgesic, etc., and at the same time, the mechanism of action of A. annua in the prevention and treatment of liver damage, anticancer, anti-inflammatory, anti-obesity and so on has been studied. With the development of Artemisia species research, A. sacrorum has received more attention as a commonly used Artemisia species. The pharmacological effects of A. sacrorum and its active ingredients were reviewed in order to provide a basis for further utilization, quality control and new drug development.

R285.5

中醫(yī)藥國(guó)際合作專項(xiàng)(基地類項(xiàng)目)(0610-2140NF020630);釋藥技術(shù)與藥代動(dòng)力學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室(天津藥物研究院)開放課題資助項(xiàng)目(010161003)