萬年蒿 Artemisia sacrorum 是中國東北地區(qū)的習用藥材,有清熱解毒、涼血止血、止痛的功效。現(xiàn)代藥理學研究表明,萬年蒿及其有效成分在保肝、抗癌、抗腫瘤、抗炎、抗肥胖、抗菌、抗氧化、鎮(zhèn)痛等方面具有良好的藥理活性,同時對萬年蒿防治肝損傷、抗癌、抗炎、抗肥胖等的作用機制進行了研究。隨著蒿屬植物研究的深入,萬年蒿作為常用的蒿屬植物得到了更多的關注。對萬年蒿及其有效成分的藥理作用進行綜述,以期為進一步利用、質量控制以及新藥研發(fā)提供依據(jù)。

Artemisia sacrorum Ledeb. is a medicine herb used in Northeast China. It has the functions of clearing heat and detoxifying, cooling blood to stop bleeding and relieving pain. Modern pharmacological research shows that A. sacrorum and its active ingredients in hepatoprotective, anti-tumor, anti-inflammatory, anti-obesity, antibacterial, antioxidant, analgesic, etc., and at the same time, the mechanism of action of A. annua in the prevention and treatment of liver damage, anticancer, anti-inflammatory, anti-obesity and so on has been studied. With the development of Artemisia species research, A. sacrorum has received more attention as a commonly used Artemisia species. The pharmacological effects of A. sacrorum and its active ingredients were reviewed in order to provide a basis for further utilization, quality control and new drug development.

R285.5

中醫(yī)藥國際合作專項(基地類項目)(0610-2140NF020630);釋藥技術與藥代動力學國家重點實驗室(天津藥物研究院)開放課題資助項目(010161003)