為了解延胡索近21年的研究熱點及臨床研究進展，分析其未來研究趨勢，分別檢索2002年1月1日—2022年12月31日中國學術期刊全文數據庫（CNKI）、萬方數據知識服務平臺（Wanfang Data）、中文科技期刊數據庫（VIP）、中國生物醫(yī)學文獻數據庫（CBM）、PubMed、Web of Science（WOS）數據庫中收錄的延胡索研究相關的中英文學術期刊，用Endnote X9進行數據整合、去重，用VOS viewer 1.6.18軟件進行文獻計量和可視化分析。結果顯示，延胡索21年來中文文獻發(fā)表量呈波動上升趨勢，英文文獻發(fā)表量呈平穩(wěn)上升趨勢，總體數量方面中文文獻多于英文文獻；關鍵詞聚類分析顯示延胡索主要研究內容以活性成分與質量研究為主，其次是藥對配伍與組方制劑，再次是功效與臨床應用?？傮w而言，延胡索研究方向以藥物評價和動物實驗居多，而在臨床應用與臨床試驗方面的研究較少，具有完善與深入挖掘的必要性。

In order to understand the research hotspots and clinical research progress of Corydalis Rhizoma in the past 21 years, and analyze its future research trends, the Chinese Academic Journal Full Text Database (CNKI), Wanfang Data Knowledge Service Platform (Wanfang Data), Chinese Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (CBM), Pubmed were searched from January 1, 2002 to December 31, 2022, respectively. And the Chinese and English core academic journals related to Corydalis Rhizoma research included in the Web of Science (WOS) core collection database were integrated and deduplicated using endnote X9, and bibliometric and visual analysis were conducted using VOS viewer 1.6.18 software. The results show that the publication volume of Chinese literature in Corydalis Rhizoma has shown a fluctuating upward trend over the past 21 years, while the publication volume of English literature has shown a steady upward trend. Overall, there are more Chinese literature than English literature. Keyword clustering shows that the main research content of Corydalis Rhizoma currently focuses on the study of active ingredients and quality, followed by drug pair compatibility and formulation, and the third is efficacy and clinical application. Overall, the current research direction of Corydalis Rhizoma is mainly focused on drug evaluation and animal experiments, while there is relatively little research in clinical applications and trials, which is necessary for improvement and exploration. In future research, more consideration should be given to the clinical trial research of Corydalis Rhizoma.

R969.4

國家自然科學基金面上項目（81973895）；北京中醫(yī)藥大學重點攻關項目（2020-JYB-ZDGG-143-3）