為了解延胡索近21年的研究熱點(diǎn)及臨床研究進(jìn)展，分析其未來研究趨勢(shì)，分別檢索2002年1月1日—2022年12月31日中國(guó)學(xué)術(shù)期刊全文數(shù)據(jù)庫(kù)（CNKI）、萬方數(shù)據(jù)知識(shí)服務(wù)平臺(tái)（Wanfang Data）、中文科技期刊數(shù)據(jù)庫(kù)（VIP）、中國(guó)生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫(kù)（CBM）、PubMed、Web of Science（WOS）數(shù)據(jù)庫(kù)中收錄的延胡索研究相關(guān)的中英文學(xué)術(shù)期刊，用Endnote X9進(jìn)行數(shù)據(jù)整合、去重，用VOS viewer 1.6.18軟件進(jìn)行文獻(xiàn)計(jì)量和可視化分析。結(jié)果顯示，延胡索21年來中文文獻(xiàn)發(fā)表量呈波動(dòng)上升趨勢(shì)，英文文獻(xiàn)發(fā)表量呈平穩(wěn)上升趨勢(shì)，總體數(shù)量方面中文文獻(xiàn)多于英文文獻(xiàn)；關(guān)鍵詞聚類分析顯示延胡索主要研究?jī)?nèi)容以活性成分與質(zhì)量研究為主，其次是藥對(duì)配伍與組方制劑，再次是功效與臨床應(yīng)用。總體而言，延胡索研究方向以藥物評(píng)價(jià)和動(dòng)物實(shí)驗(yàn)居多，而在臨床應(yīng)用與臨床試驗(yàn)方面的研究較少，具有完善與深入挖掘的必要性。

In order to understand the research hotspots and clinical research progress of Corydalis Rhizoma in the past 21 years, and analyze its future research trends, the Chinese Academic Journal Full Text Database (CNKI), Wanfang Data Knowledge Service Platform (Wanfang Data), Chinese Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database (CBM), Pubmed were searched from January 1, 2002 to December 31, 2022, respectively. And the Chinese and English core academic journals related to Corydalis Rhizoma research included in the Web of Science (WOS) core collection database were integrated and deduplicated using endnote X9, and bibliometric and visual analysis were conducted using VOS viewer 1.6.18 software. The results show that the publication volume of Chinese literature in Corydalis Rhizoma has shown a fluctuating upward trend over the past 21 years, while the publication volume of English literature has shown a steady upward trend. Overall, there are more Chinese literature than English literature. Keyword clustering shows that the main research content of Corydalis Rhizoma currently focuses on the study of active ingredients and quality, followed by drug pair compatibility and formulation, and the third is efficacy and clinical application. Overall, the current research direction of Corydalis Rhizoma is mainly focused on drug evaluation and animal experiments, while there is relatively little research in clinical applications and trials, which is necessary for improvement and exploration. In future research, more consideration should be given to the clinical trial research of Corydalis Rhizoma.

R969.4

國(guó)家自然科學(xué)基金面上項(xiàng)目（81973895）；北京中醫(yī)藥大學(xué)重點(diǎn)攻關(guān)項(xiàng)目（2020-JYB-ZDGG-143-3）