注射用丹參多酚酸（SAFI）是以丹參為原藥材，采用現(xiàn)代工藝制備而成的中藥注射劑，其主要成分為水溶性酚酸類成分，臨床上主要用于輕中度腦卒中的治療。近年來圍繞SAFI治療缺血性腦卒中開展了大量的藥理和臨床研究，主要通過對SAFI改善腦部循環(huán)、神經(jīng)保護(hù)和抗血栓3個(gè)方面的藥理機(jī)制和臨床研究進(jìn)行總結(jié)歸納，以期為后續(xù)的作用機(jī)制研究指明方向，同時(shí)為臨床合理用藥提供依據(jù)。

Salvianolic Acids for Injection (SAFI) are traditional Chinese medicine injections prepared from Salvia miltiorrhiza by modern technology. The main components of SAFI are water-soluble phenolic acids, which are mainly used in the treatment of mild and moderate cerebral infarction. In recent years, a large number of pharmacological effects and clinical studies have been carried out around SAFI in treatment of ischemic stroke. The clinical and pharmacological studies on the improvement of brain circulation, neuroprotection and antithrombotic effects of SAFI were mainly summarized in this paper, so as to point out the direction for the subsequent research on the mechanism of action of this product and provide foundation for clinical rational application.

R286.1