[關(guān)鍵詞]
[摘要]
菲類化合物是石斛屬植物的特征成分之一,可分為簡(jiǎn)單菲、二氫菲、雙菲及菲醌(酮)等菲衍生物4種類型。綜述了金釵石斛、鐵皮石斛、束花石斛、細(xì)莖石斛、流蘇石斛、密花石斛、鼓槌石斛、曲軸石斛、石斛蘭和絨毛石斛10種石斛屬植物中毛蘭菲、鼓槌菲、杓蘭素等20個(gè)菲類活性成分,并介紹其抗肝纖維化、抗腫瘤、抗炎、抗氧化、降血糖等藥理活性,希望為該屬植物的新藥研發(fā)和臨床應(yīng)用提供參考。
[Key word]
[Abstract]
Phenanthrene compounds are one of the characteristic components of Dendrobium, which can be divided into four types of phenanthrene derivatives such as simple phenanthrene, dihydrophenanthrene, diphenanthrene and phenanthrenequinone (ketone). In this paper, we reviewed 20 phenanthrene components (such as confusarin, chrysotoxene, cypripedin, and so on) in 10 species of Dendrobium, including D. nobile, D. officinale, D. chrysanthum, D. moniliforme, D. fimbriatum, D. densiflorum, D. chrysotoxum, D. gibsonii, D. formosum and D. senile, and introduced their pharmacological activities in anti-liver fibrosis, anti-tumor, antiinflammation, anti-oxidation and hypoglycemic, hoping to provide reference for the subsequent research and development and clinical application of this genus.
[中圖分類號(hào)]
R285.5
[基金項(xiàng)目]
國(guó)家自然科學(xué)基金資助項(xiàng)目(82104316);2022年度南京市中醫(yī)藥科技專項(xiàng)(ZYYB202203)