人參不僅是我國傳統(tǒng)珍貴的中藥材，更是食療保健佳品，具有多方面抗疲勞作用。人參抗疲勞的主要活性成分包括人參多糖、寡肽和皂苷，可能通過調(diào)節(jié)糖類代謝、激活磷脂酰肌醇-3-羥激酶（PI3K）/蛋白激酶B（Akt）/哺乳動物雷帕霉素靶蛋白（mTOR）等信號通路、提高骨骼肌線粒體供能效力和加快自由基清除從而產(chǎn)生抗疲勞作用。綜述人參多糖、蛋白質(zhì)、人參皂苷類有效成分抗疲勞藥理作用機(jī)制，旨在為人參用于各類抗疲勞功能產(chǎn)品的開發(fā)應(yīng)用提供依據(jù)。

Ginseng is not only a precious traditional Chinese medicinal herb in China, but also a great food therapy and health product, with various anti fatigue effects. The main active ingredients of ginseng in anti fatigue include ginseng polysaccharides, oligopeptides, and saponins, which may regulate carbohydrate metabolism, activate phosphatidylinositol 3-hydroxykinase (PI3K)/ protein kinase B (Akt)/ mammalian target of rapamycin (mTOR) and other signaling pathways enhance the energy supply efficiency of skeletal muscle mitochondria and accelerate the clearance of free radicals, thereby producing an anti fatigue effect. Summarize the anti fatigue pharmacological mechanisms of ginseng polysaccharides, proteins, and ginsenosides, aiming to provide a basis for the development and application of ginseng in various anti fatigue functional products.

R285.5