白鮮皮來源于蕓香科植物白鮮Dictamnus dasycarpus的干燥根皮,具有清熱燥濕、祛風(fēng)解毒的功效。白鮮皮的化學(xué)成分豐富,主要成分有生物堿類、檸檬苦素類、黃酮類等,具有抗菌、抗炎、抗過敏、殺蟲、抗腫瘤、保肝、改善心血管系統(tǒng)、神經(jīng)保護(hù)等藥理作用。對白鮮皮及其有效部位和單體成分(包括白鮮皮水提物、白鮮皮醇提物、白鮮皮煎劑、白鮮堿、梣酮、黃柏酮、檸檬苦素等)的藥理作用進(jìn)行總結(jié)和歸納,為進(jìn)一步深入的藥理機(jī)制研究及開發(fā)利用提供理論依據(jù)。

The Cortex Dictamni is the dried root bark of the Dictamnus dasycarpus in the rutaceae family. The Cortex Dictamni has the effect of clearing heat and dampness, dispelling wind and detoxifying. The chemical composition of Cortex Dictamni is abundant, the main components are alkaloids, limonins, flavonoids, etc., which have antibacterial, anti-inflammatory, anti-allergic,insecticidal, anti-tumor, liver protection, improve cardiovascular system, neuroprotection and other pharmacological effects. In this paper, the pharmacological effects of Cortex Dictamni effective parts and monomer components including Cortex Dictamni aqueous extract, Cortex Dictamni ethanol extracts, Cortex Dictamni decoction, dictamnine, fraxinellone, obacunone,limonin are summarized,so as to provide a theoretical basis for further in-depth mechanism research and guidance of clinical rational drug use.

R285.5

國家重點(diǎn)研發(fā)計(jì)劃“中醫(yī)藥現(xiàn)代化”重點(diǎn)專項(xiàng)2022年度項(xiàng)目(2022YFC3502104-03)