目的 通過文獻計量學的方法,對《金匱要略》"下瘀血湯"相關(guān)文獻的關(guān)鍵詞進行可視化分析,以探索該領(lǐng)域未來的研究趨勢和熱點。方法 選取中國知識資源總庫(CNKI)、萬方數(shù)據(jù)知識服務(wù)平臺(Wanfang Data)、維普中文期刊全文數(shù)據(jù)庫(VIP)作為數(shù)據(jù)來源,以"下瘀血湯"為關(guān)鍵詞進行文獻檢索。運用VOS viewer、Cite Space (6.1.R3)和Excel軟件,檢索時間從建庫至2023年12月31日,對相關(guān)文獻的關(guān)鍵詞頻次及其聚類進行分析。結(jié)果 共篩選出321篇相關(guān)文獻用于文獻發(fā)表量及被引頻次變化趨勢分析,共篩選出267篇相關(guān)文獻用于關(guān)鍵詞聚類分析。自1978年起,關(guān)于"下瘀血湯"的文獻發(fā)表呈現(xiàn)波動趨勢,分別在1995年、2007年和2012年達到高峰。涉及9類關(guān)鍵詞聚類,共計25個關(guān)鍵詞頻繁出現(xiàn)。結(jié)論 9類關(guān)鍵詞聚類可分為從《金匱要略》原文出發(fā)的下瘀血湯的基礎(chǔ)理論探討、下瘀血湯的臨床應(yīng)用及加減用藥、下瘀血湯的現(xiàn)代作用機制研究3個研究方向。其中以中醫(yī)學"血瘀證"的科學內(nèi)核、子宮內(nèi)膜異位癥、藥流不全、肺纖維化、肝癌、中藥炮制、方劑劑型等方面為最新的中文研究熱點。

Objective Using bibliometric methods, this study conducts a visual analysis of the keywords in the literature related to "Xia Yuxue Decoction" in the "Jingui Yaolue" to explore future research trends and hotspots in this field. Methods The China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, and VIP Chinese Journal Full-text Database were selected as data sources, with "Xia Yuxue Decoction " as the keyword for literature retrieval. VOSviewer, CiteSpace (6.1. R3), and Excel software were employed for analysis. The retrieval period ranged from the establishment of the databases to December 31st, 2023. The frequency of keywords and their clustering in the relevant literature were analyzed. Results A total of 321 relevant literatures were selected for analysis of publication volume and citation frequency trends, while 267 relevant literatures were used for keyword clustering analysis. Since 1978, literature on "Xia Yuxue Decoction" showed fluctuating trends in publication, with peaks in 1995, 2007, and 2012. Nine categories of keyword clusters were identified, with a total of 25 keywords appearing frequently. Conclusion The nine categories of keyword clusters can be divided into three research directions:theoretical exploration of "Xia Yuxue Decoction" based on the original text of the "Jingui Yaolue" clinical applications and modifications of "Xia YuXue Decoction" and modern mechanistic studies of "Xia Yuxue Decoction" Among them, the scientific core of traditional Chinese medicine "blood stasis syndrome," endometriosis, incomplete medication-induced abortion, pulmonary fibrosis, liver cancer, traditional Chinese medicine processing, and formulation types are the latest research hotspots.

R286.2;R289

國家自然科學基金資助項目(82074294);國家中醫(yī)藥管理局第五批全國中醫(yī)臨床優(yōu)秀人才研修項目(國中醫(yī)藥人教函[2022]239號)