[關(guān)鍵詞]
[摘要]
黃芩苷是從唇形科雙子葉植物黃芩Scutellaria baicalensis的干燥根中提取分離出來的一種黃酮類化合物,對黃芩苷的藥理作用及機(jī)制研究的關(guān)注度越來越高,主要具有抗病毒、抗腫瘤、抗炎、抗菌、神經(jīng)保護(hù)、抗氧化等藥理活性,還具有抗抑郁、調(diào)節(jié)免疫、安胎、降壓、鎮(zhèn)痛等藥理作用。為更充分開發(fā)黃芩苷的藥用價值,對黃芩苷的主要藥理活性和相關(guān)作用機(jī)制進(jìn)行分類整理,旨在為黃芩苷的臨床應(yīng)用及新藥研發(fā)提供科學(xué)依據(jù)。
[Key word]
[Abstract]
Baicalin is a flavonoid compound extracted and isolated from the dried roots of Scutellaria baicalensis, a dicotyledonous plant in the family Lamiaceae. The pharmacological effects and mechanisms of baicalin have received increasing attention, mainly exhibiting antiviral, anti-tumor, anti-inflammatory, antibacterial, neuroprotective, antioxidant and other pharmacological activities. It also has pharmacological effects such as antidepressant, immune regulation, miscarriage control, blood pressure reduction, and analgesia. In order to fully develop the medicinal value of baicalin, the main pharmacological activities and related mechanisms of action of baicalin are classified and organized, aiming to provide scientific basis for the clinical application and new drug development of baicalin.
[中圖分類號]
R285.5
[基金項(xiàng)目]
國家自然科學(xué)基金資助項(xiàng)目(82360816);貴州省中醫(yī)藥管理局中醫(yī)藥、民族醫(yī)藥科學(xué)技術(shù)研究專項(xiàng)課題(QZYY-2024-188,QZYY-2021-084);貴州省中藥炮制技術(shù)傳承基地建設(shè)國家中醫(yī)藥科技項(xiàng)目[(2015)86號];貴州中醫(yī)藥大學(xué)研究生教育創(chuàng)新計(jì)劃項(xiàng)目(YCXKYS2023034)