目的 基于文獻計量學(xué)總結(jié)國內(nèi)外仿制藥領(lǐng)域的研究現(xiàn)狀及趨勢，為進一步研究提供參考。方法 通過檢索收集中國學(xué)術(shù)期刊全文數(shù)據(jù)庫（CNKI）、Web of Science數(shù)據(jù)庫中收錄的相關(guān)文獻，借助CiteSpace6.3R2、VOSview1.6.20、文獻計量學(xué)在線分析平臺等探討本領(lǐng)域的作者機構(gòu)合作、國家合作概況，并分析關(guān)鍵詞共現(xiàn)、聚類、突現(xiàn)等，并對分析結(jié)果可視化展示。結(jié)果 共納入2 564篇文獻，其中中文文獻641篇，英文文獻1 923篇?？内厔荼砻?，國內(nèi)外仿制藥領(lǐng)域研究的發(fā)展趨勢基本相同。目前本領(lǐng)域研究已有國際化趨勢，但我國的國際合作中心性為0。關(guān)鍵詞分析顯示，國內(nèi)外仿制藥領(lǐng)域研究內(nèi)容在保持一致的前提下各有側(cè)重，其研究內(nèi)容與熱點可相互補充借鑒。結(jié)論 系統(tǒng)分析了2000—2024年間仿制藥領(lǐng)域的相關(guān)文獻，總結(jié)了目前全球仿制藥領(lǐng)域的研究現(xiàn)狀及趨勢，并進一步指出國內(nèi)外研究的異同，可為本領(lǐng)域的進一步研究提供指導(dǎo)。

Objective To explore and summarize the research status and trends in the field of generic drug both at home and abroad based on bibliometrics, and provide certain references for the further research in this field. Methods The relevant articles were searched and collected from China National Knowledge Infrastructure and Web of Science, and CiteSpace6.3R2, VOSview1.6.20, and bibliometric online analysis platforms were utilized to explore the author (institution) cooperation and national cooperation in this field, and visualize the analysis results of keyword co-occurrence, clustering and emergence. Results A total of 2 564 articles were included, including 641 Chinese and 1 923 English articles. The trend of publication indicated that the development trend of this field was basically the same. At present, there was a trend of international cooperation in this field, but the centrality of international cooperation in China was zero. The results of keyword analysis implied that the research content in this field had their own focus while maintaining consistency, which could complement and draw on each other. Conclusion This study systematically analyzes the relevant articles in the field of generic drug from 2000 to 2024, summarizes the current research status and trends as well, and further pointes out the similarities and differences between domestic and foreign research, which can provide guidance for the further research in this field.

R914

湖北省衛(wèi)生健康委聯(lián)合基金（WJ2019H181）；湖北省自然科學(xué)基金（2022CFD060）；中國藥學(xué)會全國醫(yī)藥經(jīng)濟信息網(wǎng)科普研究重點項目（CMEI2020KPYJ00318）