目的 利用CiteSpace 6.1.R6軟件對2005—2024年關(guān)于中藥治療腦卒中的國內(nèi)外文獻進行文獻計量學(xué)及可視化分析，深入探討該領(lǐng)域的研究現(xiàn)狀及未來趨勢，為未來的基礎(chǔ)研究和臨床研究提供參考依據(jù)。方法 通過中國學(xué)術(shù)期刊全文數(shù)據(jù)庫（CNKI）、萬方數(shù)據(jù)庫（Wanfang）、維普生物醫(yī)學(xué)數(shù)據(jù)庫（VIP）檢索中文文獻，以及Web of Science（WOS）檢索英文文獻，對收集到的數(shù)據(jù)進行作者、機構(gòu)及關(guān)鍵詞的深入分析。結(jié)果 共檢索到中文文獻1 312篇和英文文獻1 582篇，其中英文文獻發(fā)文量呈現(xiàn)上升趨勢，而中文文獻發(fā)文量則相對穩(wěn)定。作者合作網(wǎng)絡(luò)分析揭示了研究團隊間的交流合作，但整體合作密度有待提高；機構(gòu)間存在廣泛的跨國與跨省合作，以國內(nèi)中醫(yī)藥大學(xué)及其附屬醫(yī)院為主要研究力量。關(guān)鍵詞共現(xiàn)分析指出，利用分子對接和網(wǎng)絡(luò)藥理學(xué)手段研究中藥治療腦卒中已成為熱點，控制氧化應(yīng)激成為治療腦卒中的重要方向，丹參、黃芪等中藥在治療中展現(xiàn)出顯著價值。結(jié)論 中藥治療腦卒中在臨床和基礎(chǔ)研究中已取得一定成果，但未來仍需加強跨領(lǐng)域合作與深入研究，以期進一步挖掘其潛力并推動該領(lǐng)域的持續(xù)發(fā)展。

Objective To conduct bibliometric and visualization analysis of domestic and international literature on traditional Chinese medicine (TCM) treatment for stroke from 2005 to 2024 using CiteSpace 6.1.R6 software. To provide insights into the current research status and emerging trends in this field, serving as a reference for future basic and clinical research. Methods Literature search was conducted across Chinese databases including China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform (Wanfang), and China Science and Technology Journal Database (VIP), as well as Web of Science (WOS) for English literature. Authors, institutions, and keywords were analyzed in depth using the retrieved data. Results A total of 1 312 Chinese articles and 1 582 English articles were retrieved. The publication volume of English articles showed an upward trend, while that of Chinese articles remained relatively stable. The author collaboration network analysis revealed interactions and cooperation among research teams, though the overall cooperation density could be improved. Extensive transnational and interprovincial collaborations were observed, with domestic universities of traditional Chinese medicine and their affiliated hospitals serving as the main research forces. The keyword co-occurrence analysis indicated that utilizing molecular docking and network pharmacology to study TCM treatment for stroke has become a research hotspot, and controlling oxidative stress emerged as a crucial direction in stroke treatment. TCM such as Salviae Miltiorrhizae Radix et Rhizoma and Astragali Radix have demonstrated significant value in treatment. Conclusion TCM treatment for stroke has achieved certain accomplishments in both clinical and basic research. However, future endeavors should focus on strengthening cross-disciplinary collaboration and in-depth research to further tap into its potential and propel sustainable development in this field.

R971

國家自然科學(xué)基金青年項目（82301725）；中國博士后科學(xué)基金第73批面上資助項目（2023M732155）；山西省基礎(chǔ)研究計劃面上項目（202203021212028）；山西省衛(wèi)生健康委中醫(yī)藥科研項目（2023ZYYC2034，2024ZYYB054）；山西省高等學(xué)校科技創(chuàng)新項目（2022L132）；山西省科技廳基礎(chǔ)研究項目（20210302124586）；山西省歸國留學(xué)人員資助項目（2023-177）；山西省高等學(xué)校科技創(chuàng)新項目資助項目（2023W185）