目的 運(yùn)用CiteSpace軟件對蒼術(shù)Atractlodis Rhizoma的研究熱點(diǎn)及發(fā)展趨勢進(jìn)行可視化分析，為其深入研究提供參考。方法 分別檢索中國學(xué)術(shù)期刊全文數(shù)據(jù)庫（CNKI）、Web of Science數(shù)據(jù)庫中收錄的，2003年1月1日—2024年12月31日蒼術(shù)相關(guān)研究文獻(xiàn)，運(yùn)用CiteSpace 6.3.R1軟件對發(fā)文作者、研究機(jī)構(gòu)、關(guān)鍵詞共現(xiàn)、關(guān)鍵詞突現(xiàn)等內(nèi)容進(jìn)行可視化圖譜分析，并對蒼術(shù)研究現(xiàn)狀及發(fā)展趨勢進(jìn)行分析歸納。結(jié)果 篩選后共納入861篇中文文獻(xiàn)，339篇英文文獻(xiàn)，中、英文文獻(xiàn)年發(fā)文量均呈震蕩波動(dòng)上升趨勢；《中成藥》《Journal of Ethnopharmacology》分別是發(fā)表中文和英文文獻(xiàn)最多的期刊，劉艷菊、Dai Chuanchao分別是發(fā)表中文和英文文獻(xiàn)最多的作者，發(fā)文量較高的研究機(jī)構(gòu)為中國中醫(yī)科學(xué)院（China Academy of Chinese Medical Sciences）、湖北中醫(yī)藥大學(xué)、南京中醫(yī)藥大學(xué)、南京師范大學(xué)（Nanjing Normal University），機(jī)構(gòu)間形成一定合作規(guī)模；關(guān)鍵詞分析顯示，頻次較高且中介中心性較強(qiáng)的關(guān)鍵詞有“蒼術(shù)”“蒼術(shù)素”“茅蒼術(shù)”“ expression”“rhizomes”“apoptosis”等，中文關(guān)鍵詞研究熱點(diǎn)聚焦于傳統(tǒng)中藥的品種鑒別、道地性特征及藥效物質(zhì)基礎(chǔ)；英文關(guān)鍵詞研究熱點(diǎn)則集中于分子機(jī)制探索、細(xì)胞生物學(xué)效應(yīng)及活性成分的藥理作用路徑。關(guān)鍵詞共生成19個(gè)聚類歸納出以下5個(gè)研究熱點(diǎn)：蒼術(shù)資源與種植、質(zhì)量評價(jià)與鑒別、炮制相關(guān)與機(jī)制研究、藥理作用與機(jī)制研究、臨床應(yīng)用及配伍療效。結(jié)論 現(xiàn)階段已對蒼術(shù)功效、藥理作用、炮制機(jī)制和栽培種植等方面進(jìn)行深入研究，但仍在持續(xù)發(fā)展階段，特別是在蒼術(shù)種植栽培、炮制降燥增效機(jī)制、臨床療效評價(jià)等方面，研究尚存在不足，未來仍有較大的完善空間與深度挖掘價(jià)值。

Objective To research hotspots and development trends of Cangzhu (Atractylodis Rhizoma), so as to provide references for in-depth investigations into this medicinal herb. Methods Literature related to Atractylodis Rhizoma published between January 1, 2003, and December 31, 2024, was retrieved from the China National Knowledge Infrastructure (CNKI) and Web of Science databases. Using CiteSpace 6.3.R1 software, the data were systematically organized and visually analyzed to generate co-authorship networks, institutional collaboration maps, keyword co-occurrence clusters, and bursty keyword detection. This study synthesizes the current research landscape and future trends in Atractylodis Rhizoma research, providing a comprehensive reference for in-depth investigations. Results A total of 861 Chinese literatures and 339 English literatures were included through screening. The annual number of published papers shows an oscillating upward trend. Chinese Journal of Traditional Patent Medicine and Journal of Ethnopharmacology were the journals with the most publications in Chinese and English, respectively. Liu Yanju and Dai Chuanchao were the authors with the most publications in Chinese and English, respectively. The research institutions with high publication volumes included China Academy of Chinese Medical Sciences, Hubei University of Chinese Medicine, Nanjing University of Chinese Medicine, and Nanjing Normal University, forming a certain scale of cooperation among institutions. Keyword analysis showed that keywords with high frequency and strong betweenness centrality included "Cangzhu", "Atractylodin", "Atractylodes lancea", "expression", "rhizome", "apoptosis", etc. The research hotspots of Chinese keywords focused on the variety identification, genuine characteristics, and pharmacodynamic material basis of traditional Chinese medicine, while the research hotspots of English keywords concentrated on the exploration of molecular mechanisms, cell biological effects, and pharmacological action pathways of active ingredients. A total of 19 clusters were generated from the keywords, which were summarized into the following 5 research hotspots: Atractylodis Rhizoma resources and cultivation, quality evaluation and identification, processing-related and mechanism research, pharmacological effects and mechanism research, clinical application and compatibility efficacy. Conclusion At present, in-depth research has been carried out on the efficacy, pharmacological effects, processing mechanisms, and cultivation of Atractylodis Rhizoma However, it is still in a stage of continuous development. Especially in aspects such as the cultivation of Atractylodis Rhizoma, the mechanism of reducing dryness and enhancing efficacy in processing, and the evaluation of clinical efficacy, There are still deficiencies in the research, and there is still considerable room for improvement and potential for in-depth exploration in the future.

R282.71

國家自然科學(xué)基金資助項(xiàng)目（82360771）；國家重點(diǎn)研發(fā)計(jì)劃“中醫(yī)藥現(xiàn)代化研究”重點(diǎn)專項(xiàng)（2023YFC3504205）；特色炮制技術(shù)規(guī)律發(fā)掘——麩制項(xiàng)目（GZY-KJS-2022-051）；中藥炮制技術(shù)傳承創(chuàng)新團(tuán)隊(duì)項(xiàng)目（CXTD22003）；中藥炮制（炆法）等關(guān)鍵技術(shù)重點(diǎn)研究室項(xiàng)目（贛中醫(yī)藥科教字〔2022〕8號(hào)）；江西省“雙千人才”計(jì)劃項(xiàng)目［贛才辦字（2019）9號(hào)］；江西省中醫(yī)藥產(chǎn)業(yè)科技創(chuàng)新聯(lián)合體產(chǎn)業(yè)鏈協(xié)同攻關(guān)項(xiàng)目（20224BBG72001）；江西省自然科學(xué)基金項(xiàng)目（20224ACB206048）；中藥炮制傳承創(chuàng)新與轉(zhuǎn)化江西省重點(diǎn)實(shí)驗(yàn)室項(xiàng)目（2024SSY07091）；建昌幫特色飲片炮制工藝及質(zhì)量標(biāo)準(zhǔn)規(guī)范化研究項(xiàng)目（JCB-202302-033）；江西省標(biāo)準(zhǔn)創(chuàng)新基地（醫(yī)藥）