目的 探討丹參滴注液對慢性腦供血不足患者腦血液流變學與凝血功能的改善作用。方法 采用前瞻性、隨機、對照研究方法，2015年10月—2017年12月選擇西安大興醫(yī)院收治的腦供血不足患者130例，根據(jù)隨機數(shù)字表法分為觀察組與對照組各65例。對照組給予依達拉奉注射液30 mg加入0.9%氯化鈉注射液100 mL中，靜脈滴注，同時給予胞磷膽堿鈉注射液0.5 g加入5%葡萄糖注射液250 mL中，靜脈滴注，2次/d。觀察組在對照組治療的基礎上給予丹參滴注液250 mL靜脈滴注，1次/d，兩組均治療觀察14 d。比較兩組療效及患者腦血液流變學和凝血功能的變化。結果 觀察組與對照組的總有效率分別為96.9%和86.2%，觀察組顯著高于對照組，差異有統(tǒng)計學意義（P<0.05）。治療后觀察組的椎動脈與基底動脈血流速度分別為（33.29±7.35）cm/s和（33.59±8.14）cm/s，對照組分別為（30.22±8.02）cm/s和（30.78±7.19）cm/s，都顯著高于治療前，同組治療前后比較差異有統(tǒng)計學意義（P<0.05）；且觀察組顯著高于對照組，差異有統(tǒng)計學意義（P<0.05）。觀察組與對照組治療后的聚集指數(shù)和纖維蛋白原都顯著低于治療前，同組治療前后比較差異有統(tǒng)計學意義（P<0.05）；治療后觀察組的以上指標數(shù)值也顯著低于對照組，差異有統(tǒng)計學意義（P<0.05）。結論 丹參滴注液輔助治療慢性腦供血不足患者能改善腦血液流變學與凝血功能，從而提高治療效果，對臨床應用具有很好的指導意義。

Objective To investigate the effects of Danshen Note drops on cerebral blood rheology and coagulation function in patients with chronic cerebral circulation insufficiency. Methods From October 2015 to December 2017, Used a prospective, randomized, controlled study method, 130 cases of patients with chronic cerebral circulation insufficiency in our hospital were selected and were equally divided into the observation group and control group with 65 patients in each group accorded randomly. The control group was given routine treatment, the observation group was given Danshen note drops treatment on the basis of the control group, the treatment cycles in the two groups were 14 d.Results the total effective rates in the observation group and the control group were 96.9% and 86.2%, respectively, and the observation group was significantly higher than that of the control group (P<0.05). After treatment, the blood flow velocity of vertebral artery and basilar artery in the observation group were (33.29 ±7.35) cm/s and (33.59 ±8.14) cm/s, respectively, and the control group were (30.22 ±8.02) cm/s and (30.78 ±7.19) cm/s, respectively, which were significantly higher than those before treatment (P<0.05), and the observation group were significantly higher than that of the control group (P<0.05). The aggregation index and fibrinogen n the observation group and the control group were significantly lower than before treatment (P<0.05), and the index values after treatment in the observation group were significantly lower than that of the control group (P<0.05).Conclusion Danshen note drops in the treatment of patients with chronic cerebral circulation insufficiency can improve cerebral blood rheology and blood coagulation function, thereby improve the therapeutic effect, and it has a good guiding significance for clinical application.