染料木黃酮是一種異黃酮類化合物，不僅存在于豆科植物中，還存在于葛根、雞血藤、山豆根等中草藥中。研究表明，染料木黃酮具有抗氧化、抗腫瘤、保護(hù)心血管、防治骨質(zhì)疏松等作用，可通過調(diào)節(jié)與細(xì)胞周期和凋亡相關(guān)的基因來抑制體內(nèi)多種腫瘤細(xì)胞的生長，還可協(xié)同化療藥物提高化療的療效。本文就染料木黃酮在腫瘤發(fā)生發(fā)展中的作用機制進(jìn)行綜述。

Genistein is an isoflavone compound that is not only found in legumes, but also in Chinese herbal medicines such as pueraria, spatholobus, and mountain bean root. Studies have shown that Genistein has anti-oxidation, anti-tumor, cardiovascular protection, prevention and treatment of osteoporosis, it can inhibit the growth of various tumor cells in vivo by regulating the genes associated with cell cycle and apoptosis, and can also improve the curative effect of chemotherapy by cooperating with chemotherapeutic drugs. This article reviews the mechanism of genistein in the development of tumors.

國家自然科學(xué)基金項目（81273636）