中藥材重金屬的污染問題已成為影響中藥廣泛應(yīng)用的主要問題。由于中草藥水煎液中基質(zhì)復(fù)雜，在脫除重金屬的同時，還要保證對其有效成分不產(chǎn)生影響，脫除難度大大增加。目前去除中藥材中重金屬的方法有吸附法（大孔樹脂、γ-巰丙基鍵合硅膠、殼聚糖等）和超臨界CO₂絡(luò)合萃取法。著眼于中藥材中重金屬的脫除方法，對文獻(xiàn)報道的脫除方法進(jìn)行歸納總結(jié)，為今后中藥重金屬脫除方法及材料的開發(fā)提供借鑒。

The pollution of heavy metals in Chinese medicinal materials (CMM) has become a major problem affecting its wide application. Because of the complex matrix in the decoction of TCMM, it is almost impossible to remove the heavy metal meanwhile the active ingredients could not be affected. At present, methods for removing heavy metals in CMM include adsorption methods (macroporous resin, γ-mercaptopropyl bonded silica, chitosan) and supercritical CO₂ complex extraction. This manuscript focuses on the removal of heavy metals in CMM, and summarizes the methods reported in the literature, which provides a reference for the future development of heavy metal removal methods and materials.

中國醫(yī)學(xué)科學(xué)院醫(yī)學(xué)與健康科技創(chuàng)新工程經(jīng)費資助（2017-I2M-1-013）