2=5.000, P=0.025); Before treatment, the expression level of RRM1 in the two groups of patients had no significant difference; After treatment, the observation group the expression level of RRM1 was lower than that of the control group (t=5.545, P<0.001); There was no significant difference in the level of tumor markers between the two groups before treatment. After treatment, the levels of CEA, CYFRA21-1, CA19-9 and CA125 in the observation group were lower than those in the control group (P<0.001). Two groups of patients with hematologic and gastrointestinal toxicity, liver and kidney function damage rate had no significant difference (χ2=0.082, P=0.775). Conclusion Endostar combined with cisplatin has a good therapeutic effect on lung cancer patients with malignant pleural effusion, can significantly improve the patient's tumor markers and the expression level of RRM1, has good application value."/>

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首頁 > 過刊瀏覽>2019年第42卷第5期 >2019,42(5):944-948. DOI:10.7501/j.issn.1674-6376.2019.05.026
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重組人血管內(nèi)皮抑制素注射液聯(lián)合順鉑對肺癌合并惡性胸腔積液的療效研究

Analysis of expression level influence and clinical efficacy of Endostar combined with cisplatin on malignant pleural effusion of lung cancer RRM1

發(fā)布日期:2019-05-31
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