[關(guān)鍵詞]
[摘要]
近5年來中藥界學(xué)人發(fā)現(xiàn)22種中藥成分可有效保護內(nèi)皮祖細胞(EPCs)。分別通過調(diào)節(jié)氧化應(yīng)激反應(yīng)、抑制EPCs凋亡、阻遏炎癥因子的分泌、增強EPC動員、遷移、分化等生物學(xué)功能發(fā)揮對EPCs的保護作用。對此做系統(tǒng)論述及整理,并總結(jié)目前研究中存在的問題及以后的研究方向。
[Key word]
[Abstract]
In the past five years, Chinese medicine scholars have newly discovered 22 traditional Chinese medicine ingredients to effectively protect endothelial progenitor cells.They can protect EPCs by regulating oxidative stress response,inhibiting apoptosis of EPCs, suppressing the secretion of inflammatory factors,and enhancing the biological functions of EPC mobilization, migration and differentiation. This paper makes a systematic discussion and collation, and summarizes the existing problems and future research directions.
[中圖分類號]
[基金項目]
國家自然科學(xué)基金項目(81173164及81573852);山東省教育廳高等學(xué)??蒲许椖浚↗10LF54)