黃皮樹Phellodendron chinense、黃檗P.amurense的干燥樹皮分別作為黃柏、關(guān)黃柏入藥，二者在2005、2010、2015年版《中國藥典》被分別收錄。從這兩種藥材中分離出來的化學(xué)成分主要包括生物堿類、檸檬苦素類、酚酸類、萜類、苯丙素類、揮發(fā)性類等，具有抗菌、抗癌、抗糖尿病、保護(hù)心腦血管等多種生物活性。綜述近年來對黃柏、關(guān)黃柏化學(xué)成分、生物活性的研究進(jìn)展，為進(jìn)一步研究兩者藥效物質(zhì)基礎(chǔ)、藥理作用及臨床合理用藥提供參考依據(jù)。

The original plant of Phellodendri Chinensis Cortex was Phellodendron chinense, and the original plant of Phellodendri Amurensis Cortex was P. amurense. The two kinds of medicinal materials were recorded in the Pharmacopoeia of China in the 2005, 2010, 2015 edition as different species, and the chemical constituents isolated from the two medicinal materials mainly include alkaloids, limonoids, phenolic acids, terpenoids, phenylpropanoids, volatiles. They had many biological activities, such as antibacterial, anti-cancer, anti-diabetes, protection of cardiovascular and cerebrovascular. Recent advances in chemical constituents and biological activities of Phellodendri Chinensis Cortex and Phellodendri Amurensis Cortex were reviewed, which could provide references for further study on the pharmacodynamic material basis, pharmacological effects and rational clinical use of drugs with Phellodendri Chinensis Cortex and Phellodendri Amurensis Cortex.

中央本級重大增減支項(xiàng)目（2060302）；國家中醫(yī)藥優(yōu)勢特色教育培訓(xùn)基地（中藥）資助項(xiàng)目（J20164811007）