[關(guān)鍵詞]
[摘要]
目的 研究芪參益氣滴丸聯(lián)合尿激酶對心肌梗死患者血脂水平和左心室功能的影響。方法 選擇2015年1月—2017年12月新疆生產(chǎn)建設(shè)兵團第六師醫(yī)院收治的120例心肌梗死患者,隨機分為兩組。對照組單純靜脈滴注尿激酶,觀察組聯(lián)合餐后服用芪參益氣滴丸。兩組均治療8周。比較兩組的血脂水平、左心室功能和預(yù)后情況。結(jié)果 觀察組的有效率明顯高于對照組,差異有統(tǒng)計學(xué)意義(P<0.05)。兩組治療后的三酰甘油(TG)、低密度脂蛋白膽固醇(LDL-C)和總膽固醇(TC)水平均明顯降低,高密度脂蛋白膽固醇(HDL-C)水平明顯升高,同組治療前后比較差異均有統(tǒng)計學(xué)意義(P<0.05);且觀察組血脂改善更為明顯,組間差異有統(tǒng)計學(xué)意義(P<0.05)。兩組的左心室射血分數(shù)(LVEF)、左心室舒張末期內(nèi)徑(LVDs)、左心室后壁厚度(LVPWT)均較治療前明顯改善,同組治療前后比較差異有統(tǒng)計學(xué)意義(P<0.05);且觀察組更為明顯,組間差異有統(tǒng)計學(xué)意義(P<0.05)。觀察組的再梗死、心源性休克、心律失常和心絞痛發(fā)生率均明顯低于對照組,差異有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論 芪參益氣滴丸聯(lián)合尿激酶有助于提高心肌梗死患者的治療效果,改善血脂水平、左心室功能和預(yù)后情況,值得應(yīng)用推廣。
[Key word]
[Abstract]
Objective To investigate the effect of Qishen Yiqi Dripping Pills combined with urokinase on blood lipid level and left ventricular function in patients with myocardial infarction.Methods Selected 120 cases of patients with myocardial infarction who were treated in Xinjiang Production and Construction Corps Agricultural Construction Sixth Division from January 2015 to December 2017, divided into two groups randomly. The control group was intravenously injected with urokinase, and the observation group received Qishen Yiqi Dripping Pills after meals. Results After treatment, the effective rate of the observation group was significantly higher than control group (P<0.05). The levels of TG, LDL-C and TC in the two groups were significantly decreased (P<0.05), and the HDL-C level increased significantly (P<0.05), and the observation group was more significant (P<0.05). The LVEF, LVDs and LVPWT were significantly improved (P<0.05), and the observation group was more obvious (P<0.05). The incidence of reinfarction, cardiogenic shock, arrhythmia and angina pectoris in the observation group were significantly lower than those in the control group (P<0.05).Conclusion Qishen Yiqi Dripping Pills combined with urokinase can improve the therapeutic effect, improve blood lipid level, left ventricular function and prognosis in patients with myocardial infarction.
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