中藥血清藥物化學(xué)是通過對(duì)實(shí)驗(yàn)動(dòng)物口服給藥后的含藥血清進(jìn)行分析，對(duì)藥效物質(zhì)基礎(chǔ)及復(fù)方配伍機(jī)制進(jìn)行快速篩選的一項(xiàng)新型技術(shù)，在中藥質(zhì)量控制、中藥炮制研究等領(lǐng)域都發(fā)揮重要作用。隨著不斷的發(fā)展創(chuàng)新，將其與血清藥理學(xué)、藥動(dòng)學(xué)等學(xué)科相互融合，為中藥及復(fù)方的研究提供了更加完善的手段。對(duì)中藥血清藥物化學(xué)的主要技術(shù)手段、應(yīng)用研究及其與一些學(xué)科的聯(lián)合使用現(xiàn)狀進(jìn)行綜述，為中藥血清藥物化學(xué)的發(fā)展提供新的研究思路。

Serum pharmacochemistry of traditional Chinese medicine (TCM) is a new technique for rapid screening of effective material basis and compound compatibility mechanism by analyzing the serum containing drugs after oral administration in experimental animals. It plays an important role in the quality control of traditional Chinese medicine, the processing of traditional Chinese medicine and other fields. With the continuous development and innovation, it is integrated with serum pharmacology, pharmacokinetics and other disciplines, which provides a more perfect means for the study of traditional Chinese medicine and compound prescription. In this paper, the main technical means and applied research of serum pharmacochemistry of traditional Chinese medicine and its combined use with some disciplines are reviewed, which provides a new research idea for the development of serum pharmacochemistry of traditional Chinese medicine.With the continuous development and innovation, it is integrated with serum pharmacology, pharmacokinetics and other disciplines, which provides a more perfect means for the study of traditional Chinese medicine and compound prescription. In this paper, the main technical means and applied research of serum pharmacochemistry of traditional Chinese medicine and its combined use with some disciplines are reviewed, which provides a new research idea for the development of serum pharmacochemistry of traditional Chinese medicine.

山西省重點(diǎn)研發(fā)項(xiàng)目（項(xiàng)目編號(hào)：201603D321028）