探討了四逆湯對(duì)缺血（氧）心電圖的影響及其可能的作用機(jī)制。結(jié)果表明：四逆湯對(duì)垂體后葉素引起的家兔缺血性心電圖有顯著的改善作用，S－T段的下移顯著減輕、T波的增高明顯受到抑制；四逆湯也顯著延長(zhǎng)了缺氧小鼠的心電活動(dòng)時(shí)間，四逆湯對(duì)缺血（氧）心肌的此種保護(hù)作用可能與其顯著增加心肌營(yíng)養(yǎng)血流量有關(guān)。

Effects of Sini decoction(SD)on ischemic(anoxic)electrocardiogram(ECG)and poss- ible action mechanism of SD were studied。 Results indicate that SD significantly improves the pituitrin induced ischemic ECG of rabbits, significantly prevents S-T segment from desconding and suppresses the elevation of T wave, SD can also lengthen significantly cardioe lectric activity time of anoxic mice, The protective effects of SD on ischemic(anoxic)myocardium may be related to the signif:canl increase of myocardial nutritional blood flow induced by administrating SD,

國(guó)家中醫(yī)藥管理局重點(diǎn)課題