首次對(duì)紫色懸鉤子 Rubus irritans Focke和菰帽懸鉤子R.pileatus Focke的化學(xué)成分進(jìn)行了研究。從其地上部分的乙醇提取物經(jīng)各種柱層析方法分離純化分別得到６個(gè)和５個(gè)化合物,運(yùn)用光譜方法和與標(biāo)準(zhǔn)品對(duì)照分別鑒定為：2α,3β,19α-三羥基烏索-12-烯-28-酸(Ⅰ),2α,3β,19α,23-四羥基烏索-12-烯-28-酸(Ⅱ),2α,3β,19α,23-四羥基齊墩果-12-烯-28-酸(Ⅲ),2α,3β,19α,24-四羥基烏索-12-烯-28-酸(Ⅳ),３β,１９α-二羥基烏索-１２-烯-24,28-二酸(Ⅴ),烏索酸(Ⅵ),齊墩果酸(Ⅶ),卜胡蘿卜苷(Ⅷ)和β-Ｄ-(-)-吡喃果糖(Ⅸ)。這些化合物均為首次從該兩種植物中分得。

Six and five compounds have been isolated respectively from Purple Raspberry (Rubus irritan Focke) and Capform Raspberry (Rubus pileatus Focke). Based on chemical and spectral evi dences,or by comparison with authentic samples,the structures of these compounds were elucidated as 2a, 3p,19a-trihy-droxyurs-l2-en-28-oic acid(I),2a, 3β, 19a, 23-tetrah ydroxyurs-12-en-28-oic acid(Ⅱ),2a, 3β, 19a, 23-tetrahydroxyolean-l2-en-28-oic acid( Ⅲ),2a, 3β, 19a, 24-tetrahydroxyurs-12-en-28-oic acid(Ⅲ),3β, 19a-dihydroxyurs-12-en-24, 28-dioic acid( V),ursolic acid(VI),oleanolic acid(Ⅶ),daucosterol (Ⅷ),and (β-D-pyranofructose(Ⅸ).All these compounds were isolated for the first time from these two species of Rubus L.

國(guó)家自然科學(xué)基金;蘭州大學(xué)應(yīng)用有機(jī)化學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室資助