目的 從豆科葛屬植物云南葛藤Pueraria peduncularis中分離得到10個(gè)化合物。方法 通過波譜和化學(xué)方法分別進(jìn)行鑒定。結(jié)果 它們的化學(xué)結(jié)構(gòu)為:3-O-[β-D-吡喃葡萄糖(1→3)-β-D-吡喃葡萄糖醛酸甲酯苷]-3β,15α,23-三羥基齊墩果-12-烯-16-酮(Ⅰ),大豆素(Ⅱ),染料木素(Ⅲ),大豆苷(Ⅳ),染料木苷(Ⅴ),3β,15α-二羥基齊墩果-12-烯-16-酮(Ⅵ),羽扇醇(Ⅶ),樺木酸(Ⅷ),α-菠甾醇葡萄糖苷(Ⅸ)和α-菠甾醇(Ⅹ)。結(jié)論 化合物Ⅰ對黑曲霉具有抑制活性。

Object To investigate the chemical constituents from the stem of Pueraria peduncularis (Grah. ex Benth.) Benth. Methods The constituents were isolated on silica gel column chromatography. Their structures were elucidated by chemical and spectroscopic evidence. Results Ten compounds were comfirmed as 3-O-D-glucopyranosyl-(1→3)-β-D-6-O-methyl-glucuronopyranosyl]-3β, 15α, 23-trihydroxy-olean-12-en-16-one (Ⅰ), daidzein (Ⅱ), genistein (Ⅲ), daidzin (Ⅳ), genistin (Ⅴ), 3β, 15α-dihydroxy-olean-12-en-16-one (Ⅵ), lupeol (Ⅶ), betulinic acid (Ⅷ), α-spinasterol-glucopyranoside (Ⅸ) and α-spinasterol (Ⅹ). -3β, 15α, 23-trihydroxy-olean-12-en-16-one (Ⅰ), daidzein (Ⅱ), genistein (Ⅲ), daidzin (Ⅳ), genistin (Ⅴ), 3β, 15α-dihydroxy-olean-12-en-16-one (Ⅵ), lupeol (Ⅶ), betulinic acid (Ⅷ), α-spinasterol-glucopyranoside (Ⅸ) and α-spinasterol (Ⅹ). Conclusion Compound Ⅰ exhibited antimicrobial activity against Aspergillus niger. Compounds Ⅱ-Ⅹ were first isolated from this plant.