[關(guān)鍵詞]
[摘要]
以柴胡、款冬花、遠(yuǎn)志等山西道地中藥材為例,總結(jié)植物代謝組學(xué)技術(shù)在中藥材質(zhì)量評(píng)價(jià)中的應(yīng)用。在中藥材質(zhì)量評(píng)價(jià)中,代謝組學(xué)側(cè)重于對(duì)樣本的客觀分組聚類,同時(shí)可確定差異代謝物,與指紋圖譜技術(shù)具有明顯的互補(bǔ)性,可使中藥質(zhì)量標(biāo)準(zhǔn)更體現(xiàn)中藥特色,提高其可控性。分析該技術(shù)的優(yōu)勢(shì)與應(yīng)用前景,指出尚存在的問(wèn)題和改進(jìn)建議,為擴(kuò)大其應(yīng)用提供參考。
[Key word]
[Abstract]
The application of plant metabolomic technology in the quality evaluation of traditional Chinese medicinal materials (TCMM) was reviewed, using Buplerui Radix, Farfarae Flos, Polygale Radix, and Astragali Radix as genuine medicinal materials. In quality evaluation of TCMM, not only the cluster, but also the differential metabolites between different groups could be revealed simultaneously by metabolomic technology. Thus, plant metabolomic technology is complimentary with fingerprint technology, the characteristics of TCMM could be reflected in quality standards, and the controllability could be also improved. The advantage as well as the prospect is discussed. In addition, the limitations of this technique are pointed and the improvement methods are also suggested.
[中圖分類號(hào)]
[基金項(xiàng)目]
國(guó)家自然科學(xué)基金資助項(xiàng)目(31270008,30570174,30900118,31070295,31100244,30710103092);山西省國(guó)際科技合作(2010081070,2008081043)