目的 研究石菖蒲Acorus tatarinowii根莖的化學(xué)成分。方法 利用不同的色譜分離純化方法，并通過理化性質(zhì)和波譜技術(shù)鑒定化合物結(jié)構(gòu)。結(jié)果 從石菖蒲根莖90%乙醇提取液中分離得到13個(gè)化合物，分別鑒定為反式丁烯二酸（1）、煙酸（2）、對(duì)羥基苯甲酸（3）、尿嘧啶（4）、N-反式-對(duì)羥基苯乙基香豆酰胺（5）、胸腺嘧啶（6）、兩型曲霉醌A（7）、丁二酸（8）、石菖蒲醇（9）、石菖蒲醇-12-β-D-葡萄糖苷（10）、β-谷甾醇（11）、2, 5-二甲氧基對(duì)苯醌（12）、5-羥甲基糠醛（13）。結(jié)論 化合物1～7均為從菖蒲屬植物中首次分離得到。

Objective To study the chemical constituents from the roots and rhizomes of Acorus tatarinowii. Methods Using different chromatographic methods to isolate and purify the constituents of A. tatarinowii, and their structures were identified by physicochemical properties and spectroscopic technology. Results Thirteen compounds were isolated and identified as fumaric acid (1), nicotinic acid (2), p-hydroxybenzonic acid (3), uracil (4), N-trans-feruloyltyramine (5), thymine (6), variecolorquinone A (7), butanedioic acid (8), tatarol (9), tataroside-12-β-D-glucoside (10), β-sitosterol (11), 2, 5-dimethoxy- benzoquinone (12), and 5-hydroxymethyl-2-furaldehyde (13). Conclusion Compounds 1—7 are isolated from the plants in Acorus L. for the first time.

國家自然科學(xué)基金面上項(xiàng)目（81173510）；“十二五”國家科技重大創(chuàng)新藥物專項(xiàng)（2011ZX09102-101-01，2012ZX09301-002-001）