目的 優(yōu)選不同輔料膏方制備工藝的最佳條件參數(shù)。方法 以膏方的性狀特征、成膏率及藥材檢出情況為控制指標(biāo)，采用多指標(biāo)綜合評(píng)分法評(píng)價(jià)膏方成型性；以輔料的使用量（A）、清膏（B）和成品膏（C）的相對(duì)密度為3個(gè)因素，采用星點(diǎn)設(shè)計(jì)進(jìn)行試驗(yàn)，優(yōu)選膏方制備工藝。結(jié)果 4種不同輔料膏方的制備工藝分別為紅糖：A₁ 18%～23%、B₁ 1.210～1.260、C₁ 1.310～1.360；鹿角膠：A₂ 14%～16%、B₂ 1.200～1.250、C₂ 1.230～1.270；龜甲膠：A₃ 12%～15%、B₃ 1.190～1.230、C₃ 1.210～1.240；阿膠：A₄ 5.0%～8.0%、B₄ 1.190～1.220、C₄ 1.190～1.220。結(jié)論 優(yōu)選的不同輔料的膏方制備工藝參數(shù)均準(zhǔn)確可行，質(zhì)量符合要求。

Objective To explore the best parameter in the preparation technology of paste with different adjuvants. Methods The appearance, the paste rate, and herb detection were selected as composite indicators. The multi-index comprehensive score method was used to evaluate the paste formability. Central composite design was used to optimize the preparation technology of paste by taking the adjuvant amount (A), the relative density of extract (B) and refined paste (C) as factors. Results The best condition in the paste preparation process with different adjuvants was as follows: brown sugar (A₁ 18%—23%, B₁ 1.210—1.260, and C₁ 1.310—1.360), Cervi Cornus Colla (CCC, A₂ 14%—16%, B₂ 1.200—1.250, and C₂ 1.230—1.270), Testudinis Carapacis et Plastri Colla (TCPC, A₃ 12%—15%, B₃ 1.190—1.230, and C₃ 1.210—1.240), Asini Corii Colla (ACC, A₄ 5.0%—8.0%, B₄ 1.190—1.220, and C₄ 1.190—1.220). Conclusion The parameters in the preparation technology of the paste with different adjuvants are accurate and feasible and the quality meets the requirement.