目的 研究延齡草Trillium tschonoskii根及根莖中的化學成分。方法 采用硅膠、聚酰胺、反相硅膠C₁₈和Sephadex LH-20柱色譜對延齡草70%乙醇提取物進行分離純化。用質(zhì)譜、核磁等波譜學方法確定化合物結(jié)構(gòu)。結(jié)果 從延齡草醋酸乙酯和正丁醇部位分離得到12個化合物，分別鑒定為β-蛻皮激素（1）、pinnatasterone（2）、polypodine B（3）、3-甲氧基-4-羥基-苯丙酸甲酯（4）、岷江百合苷A（5）、4-羥基苯甲酸（6）、香草醛（7）、β-D-吡喃葡萄糖基(1→4)-O-[α-L-吡喃鼠李糖基 (1→2)]-O-β-D-吡喃葡萄糖苷（8）、重樓皂苷V（9）、重樓皂苷III（10）、延齡草苷A（11）、延齡草苷C（12）。結(jié)論 化合物1、2、6、7、9、10首次從該屬植物中分離得到，化合物3～5、11、12首次從該種植物中分離得到。

Objective To investigate the chemical constituents in the roots and rhizomes of Trillium tschonoskii. Methods The roots and rhizomes of T. tschonoskii were extracted with 70% ethanol and separated by chromatography on polyamide, silica gel, RP-C₁₈, and Sephadex LH-20 columns. Chemical structures were identified by MS, 1D and 2D NMR experiments. Results Twelve compounds were isolated and identified from the ethyl acetate extract from the roots and rhizomes of T. tschonoskii and n-butanol fractions were identified as β-ecdysone (1), pinnatasterone (2), polypodine B (3), methyl ferulorate (4), regaloside A (5), 4-hydroxy- benzoic acid (6), vanillic aldehyde (7), β-D-glucopyranosyl-(1→4)-O-[α-L-rhamnopyranosyl-(1→2)]-O-β-D-glucopyranoside (8), paris saponin V (9), paris saponin III (10), trillenoside A (11), and trillenoside C (12). Conclusion Compounds 1, 2, 6, 7, 9, and 10 are isolated from the plants in this genus for the first time, and compounds 3—5, 11, and 12 are isolated from this plant for the first time.

國家自然科學基金資助項目（81260631）