[關(guān)鍵詞]
[摘要]
細(xì)胞因子風(fēng)暴是機(jī)體對(duì)外界刺激產(chǎn)生的一種過激免疫反應(yīng),其發(fā)病機(jī)制復(fù)雜、疾病進(jìn)展迅速、死亡率高。在此次新型冠狀病毒肺炎(COVID-19)疫情中,患者病情急劇惡化與體內(nèi)爆發(fā)的細(xì)胞因子風(fēng)暴密切相關(guān),《新型冠狀病毒感染的肺炎診療方案(試行第六版)》亦給出了中醫(yī)藥治療方案。從細(xì)胞因子風(fēng)暴的源頭、過程、危害出發(fā),綜述了中藥在抗原清除、免疫調(diào)節(jié)、組織保護(hù)等方面的藥理作用,探討了中西醫(yī)結(jié)合臨床治療多種肺炎的優(yōu)勢(shì),闡明了中藥對(duì)防治細(xì)胞因子風(fēng)暴的貢獻(xiàn),為臨床治療提供有價(jià)值的用藥指導(dǎo)。
[Key word]
[Abstract]
Cytokine storm is an excessive immune process when the body is stimulated. The disease progresses rapidly with a high mortality and complicated pathogenesis. In the outbreak of coronavirus disease 2019 (COVID-19), the rapid deterioration of the condition of patient is closely related to the outbreak of cytokine storm in the body. The sixth edition of Diagnosis and Treatment of Novel Coronavirus Pneumonia also provides a traditional Chinese medicine treatment plan. This paper reviewed the pharmacological effects of traditional Chinese medicine in antigen clearance, immune modulation and tissue protection based on the source, process and harm of cytokine storm. Furthermore, traditional Chinese medicine is contributive in prevention and treatment of cytokine storm, which can provide valuable medication guidance for the treatment combining traditional Chinese and Western medicine in clinic.
[中圖分類號(hào)]
R285
[基金項(xiàng)目]