血管內(nèi)皮功能障礙是一種病理狀態(tài)，其主要表現(xiàn)為內(nèi)皮依賴性血管舒張功能下降，因調(diào)節(jié)內(nèi)皮正常功能的活性物質(zhì)合成和釋放能力發(fā)生障礙所致。血管內(nèi)皮功能障礙被認(rèn)為是冠狀動(dòng)脈硬化、高血壓、2型糖尿病血管病變的始發(fā)和進(jìn)展的關(guān)鍵危險(xiǎn)因素。通過(guò)對(duì)中西醫(yī)對(duì)血管內(nèi)皮功能障礙的認(rèn)識(shí)，中藥單體和復(fù)方治療血管內(nèi)皮功能障礙的研究現(xiàn)狀進(jìn)行綜述，旨在探討中藥治療血管內(nèi)皮功能障礙的有效性和機(jī)制。

Vascular endothelial dysfunction is a pathological state characterized by a decline in endothelium-dependent vascular relaxation function due to impaired synthesis and release of active substances that regulate endothelial normal function. It is considered a key risk factor for the onset and progression of coronary artery atherosclerosis, hypertension, and vascular lesions in type 2 diabetes mellitus. This article reviews the understanding of endothelial dysfunction in both Western and traditional Chinese medicine, as well as the current research status of single herbs and compound formulas in treating endothelial dysfunction. The aim is to explore the effectiveness and mechanisms of traditional Chinese medicine in treating endothelial dysfunction.

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國(guó)家自然科學(xué)基金資助項(xiàng)目(82305006);重慶市科研機(jī)構(gòu)績(jī)效激勵(lì)引導(dǎo)專項(xiàng)(cstc2021jxjl130002);重慶市科研機(jī)構(gòu)績(jī)效激勵(lì)引導(dǎo)專項(xiàng)(cstc2021jxjl130020);重慶市博士后創(chuàng)新人才支持計(jì)劃(CQBX2021001);博士后研究項(xiàng)目特別資助(2021XM1010)